第三腰椎骨骼肌指数在终末期肝病营养诊断中的应用价值

耿楠; 孔明; 陈煜; 段钟平

doi:10.3969/j.issn.1001-5256.2021.10.050

第三腰椎骨骼肌指数在终末期肝病营养诊断中的应用价值

DOI: 10.3969/j.issn.1001-5256.2021.10.050

首都医科大学附属北京佑安医院肝病中心四科，肝衰竭与人工肝治疗研究北京市重点实验室，北京 100069

基金项目:

国家科技重大专项"艾滋病和病毒性肝炎等重大传染病防治" (2017ZX10203201-005);

国家重点研发计划资助项目 (2017YFA0103000);

北京市医院管理局临床医学发展专项经费资助 (ZYLX201806)

详细信息

通信作者:
段钟平，duan@ccmu.edu.cn

耿楠、孔明对本文贡献相同，同为第一作者。

中图分类号: R575
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出版历程
- 收稿日期: 2021-03-15
- 录用日期: 2021-04-06
- 出版日期: 2021-10-20

Value of L3 skeletal muscle index in nutritional diagnosis of end-stage liver disease

Fourth Department of Liver Disease Center & Beijing Municipal Key Laboratory of Liver Failure and Artificial Liver Treatment Research, Beijing YouAn Hospital, Capital Medical University, Beijing 100069, China

Research funding:

National Science and Technology Key Project on "Major Infectious Diseases such as HIV/AIDS, Viral Hepatitis Prevention and Treatment" (2017ZX10203201-005);

National Key R&D Program of China (2017YFA0103000);

Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support (ZYLX201806)

摘要

摘要: 终末期肝病患者因营养摄入减少、能量消耗增加、禁食适应性受损、肝糖原储备减少、蛋白质消耗增加常导致营养不良。第三腰椎骨骼肌指数(L3-SMI)(第三腰椎横断面肌肉的面积/身高平方)是反映终末期肝病营养不良的重要指标，具有客观性强、受水钠潴留影响小、可重复性好等优点。回顾了L3-SMI在肝硬化、肝衰竭、肝癌和接受肝移植患者营养不良诊断的相关研究。分析表明，L3-SMI可系统评估终末期肝病患者营养状况和营养干预的效果，有望成为终末期肝病营养诊断的重要手段。
- 终末期肝病 /
- 营养不良 /
- 身体成分 /
- 诊断 /
- 预后
Abstract: Patients with end-stage liver disease often have malnutrition caused by reduced nutrient intake, increased energy consumption, impaired fasting adaptability, reduced liver glycogen reserve, and increased protein consumption. L3 skeletal muscle index (L3-SMI) (skeletal muscle cross-sectional area at the level of L3/square of height) is an important indicator for evaluating malnutrition in end-stage liver disease, with the advantages of strong objectivity, little influence by water-sodium retention, and good repeatability. This article reviews the application of L3-SMI in the nutritional diagnosis of liver cirrhosis, liver failure, liver cancer, and liver transplantation. The analysis shows that L3-SMI can effectively evaluate nutritional status and the effect of nutritional intervention in patients with end-stage liver disease, and therefore, it is expected to become an important method for nutritional diagnosis in end-stage liver disease.
- End Stage Liver Disease /
- Malnutrition /
- Body Composition /
- Diagnosis /
- Prognosis

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