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姓名: 朱峰
职称: 主任 主任医师
单位: 南京医科大学附属逸夫医院 普外科
简历介绍:

朱峰,男,51岁。主任医师,副教授,博士,硕士研究生导师,南京医科大学附属逸夫医院普外科主任,江苏省医学会胰腺外科学组委员,江苏省医学会胰腺病分会胰腺癌学组委员,江苏省中西医结合学会肝病专业委员会委员,南京医学会普外专业委员会委员,江苏省“333”人才,江苏省第一批“卫生拔尖人才”,吴阶平医学基金会“全国肝胆病咨询专家”。

1997年毕业于南京大学医学院(七年制),师从黎介寿院士,获外科学硕士学位,2005年在浙江大学郑树森院士指导下主攻肝脏移植,并取得外科学博士学位。长期从事肝癌、胰腺癌和器官移植方面的临床和基础研究工作。2011年8月至10月受卫生部派遣到意大利进修培训三月。曾经获得华夏医学奖三等奖1项, 江苏省卫生厅医学新技术引进二等奖2项、常州市科技进步奖二等奖1项、常州市卫生局新技术引进奖3项。参与国家自然科学基金面上项目3项,主持常州市科技局青年科技人才培养计划立项课题、常州市卫生局科研项目3项。南京市级课题1项。曾在《Am J Surg》、《Biomedicine armacotherapy》、《HBPD INT》、《 World J Gastroenterol》、《 World J Surg Oncol》、《Indian J surg》、《JOURNAL OF PROTEOMICS》、《中华肝胆外科杂志》、《中华内分泌外科杂志》、《中华胰腺病杂志》、《中国科学 C辑》、《中国普通外科杂志》、《中华急诊医学杂志》等期刊上发表论文30余篇。

发表论文:

1.Wu Jing, Liu he,Zhufeng,Xue Bin,et al. iTRAQ- basedquantitative proteomic analysis of the liverregeneration termination phase after partialhepatectomy in mice. JOURNAL OF PROTEOMICS. 2022.4 (共同通讯作者)

2.Xu Y, Gao H, Du Z, Liu H, Cheng Q, Zhang F, Ye J, Wang A, Dou Y, Ma B, Zhao N, Zhu F, Xu X, Shen N, Wu J, Xue B.  A new approach for reducing pollutants level: a longitudinal cohort study of physical exercises in young people. BMC Public Health. 2022 Feb 3;22(1):223. doi: 10.1186/s12889-022-12621-2. PMID: 35114971 Free PMC article. (共同通讯作者)

3.Duan YF, Li XD, Sun DL, Chen XM, An Y, Zhu F. A preliminary study on surgery for hepatocellular carcinoma patients with portal hypertension. Am J Surg. 2015 Jul;210(1):129-33. doi: 10.1016/j.amjsurg.2014.08.022. Epub 2014 Oct 13. PMID: 25457251(通讯作者)

4. Zhou JB, Chen WB, Zhu F. Hepatic Rupture Induced by Spontaneous Intrahepatic Hematoma.

Case Rep Surg. 2018 Jan 28;2018:2026846. doi: 10.1155/2018/2026846. eCollection 2018. PMID: 29623230 Free PMC article. (通讯作者)

5. Zhou JB, Luo BY, Liu CW, Zhu F. Effects of early antiplatelet therapy after splenectomy with gastro-oesophageal devascularization. ANZ J Surg. 2018 Oct;88(10):E725-E729. doi: 10.1111/ans.14395. Epub 2018 Feb 3. PMID: 29396900 Free PMC article. (通讯作者)

6. Cai H, An Y, Wu D, Chen X, Zhang Y, Zhu F, Jiang Y, Sun D. Laparoscopic Partial Splenectomy: A Preferred Method for Select Patients. J Laparoendosc Adv Surg Tech A. 2016 Dec;26(12):1010-1014. doi: 10.1089/lap.2016.0150. Epub 2016 Jul 28. PMID: 27467747

7. Zhu F, Duan YF, Bao WY, Liu WS, Yang Y, Cai HH. HtrA1 regulates epithelial-mesenchymal transition in hepatocellular carcinoma. Biochem Biophys Res Commun. 2015 Nov 20;467(3):589-94. doi: 10.1016/j.bbrc.2015.09.105. Epub 2015 Sep 25. PMID: 26403966

8. Bao W, Zhu F, Duan Y, Yang Y, Cai H. HtrA1 resensitizes multidrug-resistant hepatocellular carcinoma cells by targeting XIAP. Biomed Pharmacother. 2015 Mar;70:97-102. doi: 10.1016/j.biopha.2014.12.044. Epub 2015 Jan 7. 

9. Wu B, Jiang Y, Zhu F, Sun D, Huang H. Demethylation effects of elemene on the GSTP1 gene in HCC cell line QGY7703. Oncol Lett. 2016 Apr;11(4):2545-2551. doi: 10.3892/ol.2016.4243. Epub 2016 Feb 18. PMID: 27073515 Free PMC article. (通讯作者)

10. Bao WY, She G, Duan YF, Liu SY, Sun DL, Yang Y, Zhu F. Diagnosis and Management of High-Grade Pancreatic Trauma: Report of 14 Cases. Indian J Surg. 2015 Dec;77(Suppl 3):1222-6. doi: 10.1007/s12262-015-1258-z. Epub 2015 Mar 14. PMID: 27011541 Free PMC article. (通讯作者)

11. Wu CX, Bao WY, Zhu F. Enucleation is Better for a Giant Hemangioma Proximal to the Hepatic Portal Vascular Structures. Indian J Surg. 2016 Aug;78(4):304-8. doi: 10.1007/s12262-015-1382-9. Epub 2015 Nov 2. PMID: 27574349 Free PMC article. (通讯作者)

12. Duan YF, Jiang Y, Wu CX, Zhu F. Spontaneous rupture of primary splenic angiosarcoma: a case report and literature review. World J Surg Oncol. 2013 Mar 4;11:53. doi: 10.1186/1477-7819-11-53. PMID: 23497454 Free PMC article. Review. (通讯作者)

13. Wu BQ, Jiang Y, Zhu F, Sun DL, He XZ. Long Noncoding RNA PVT1 Promotes EMT and Cell Proliferation and Migration Through Downregulating p21 in Pancreatic Cancer Cells. Technol Cancer Res Treat. 2017 Dec;16(6):819-827. doi: 10.1177/1533034617700559. Epub 2017 Mar 30. PMID: 28355965 Free PMC article.

14. Duan YF, An Y, Zhu F, Jiang Y. Remote ischemic preconditioning protects liver ischemia-reperfusion injury by regulating eNOS-NO pathway and liver microRNA expressions in fatty liver rats. Hepatobiliary Pancreat Dis Int. 2017 Aug 15;16(4):387-394. doi: 10.1016/S1499-3872(17)60006-7. PMID: 28823369

15. Liu W, Zhu F, Jiang Y, Sun D, Yang B, Yan H. siRNA targeting survivin inhibits the growth and enhances the chemosensitivity of hepatocellular carcinoma cells. Oncol Rep. 2013 Mar;29(3):1183-8. doi: 10.3892/or.2012.2196. Epub 2012 Dec 18. PMID: 23254641

16. Duan YF, Li XD, Zhu F, Zhang F. Expression and clinical significance of angiotensin II type 1 receptor in human hepatocellular carcinoma. Exp Ther Med. 2014 Feb;7(2):323-328. doi: 10.3892/etm.2013.1411. Epub 2013 Nov 15. PMID: 24396398 Free PMC article.

17. Cai H, An Y, Chen X, Sun D, Chen T, Peng Y, Zhu F, Jiang Y, He X. Epigenetic inhibition of miR-663b by long non-coding RNA HOTAIR promotes pancreatic cancer cell proliferation via up-regulation of insulin-like growth factor 2. Onco target. 2016 Dec 27;7(52):86857-86870. doi: 10.18632/oncotarget.13490. PMID: 27895308 Free PMC article.

18. Duan YF, Yang B, Zhu F. Traumatic rupture of a type IVa choledochal cyst in an adult male. World J Gastroenterol. 2013 Jun 28;19(24):3911-4. doi: 10.3748/wjg.v19.i24.3911. PMID: 23840134 Free PMC article. (通讯作者)

19. Duan YF, Sun DL, Chen J, Zhu F, An Y. MicroRNA-29a/b/c targets iNOS and is involved in protective remote ischemic preconditioning in an ischemia-reperfusion rat model of non-alcoholic fatty liver disease. Oncol Lett. 2017 Mar;13(3):1775-1782. doi: 10.3892/ol.2017.5623. Epub 2017 Jan 18. PMID: 28454323 Free PMC article.

20. Duan YF, Xue W, Zhu F, Sun DL. FOCUS harmonic scalpel compared to conventional hemostasis in open total thyroidectomy - a prospective randomized study. J Otolaryngol Head Neck Surg. 2013 Dec 20;42(1):62. doi: 10.1186/1916-0216-42-62. PMID: 24359618 Free PMC article. Clinical Trial.

21. Duan YF, Zhu F, Li XD, An Y, Zhang H, Zhou Y, Zhang X, Jiang Y. Association between ABO gene polymorphism (rs505922) and cancer risk: a meta-analysis. Tumour Biol. 2015 Jul;36(7):5081-7. doi: 10.1007/s13277-015-3159-y. Epub 2015 Feb 6. PMID: 25656610

22. Wu BQ, Zhu F, Jiang Y, Sun DL. 31 Case of spontaneous splenic rupture caused by ectopic pregnancy in the spleen. J Obstet Gynaecol Res. 2017 Nov;43(11):1778-1780. doi: 10.1111/jog.13440. Epub 2017 Aug 1. PMID: 28762583

23. Zhu F, Jin L, Luo TP, Luo GH, Tan Y, Qin XH. Serine protease HtrA1 expression in human hepatocellular carcinoma. Hepatobiliary Pancreat Dis Int. 2010 Oct;9(5):508-12. PMID: 20943460

24. Duan YF, Tan Y, Yuan B, Zhu F. Spontaneous rupture of hepatic metastasis from small cell neuroendocrine carcinoma of maxillary sinus. World J Surg Oncol. 2014 Apr 27;12:126. doi: 10.1186/1477-7819-12-126. PMID: 24767405 Free PMC article. (通讯作者)

25. Xu YJ, Gao HL, Liu H, Zhao NW, Cheng Q, Zhang FR, Ye J, Wang AQ, Dou YJ, Ma B, Zhu F, Xu XL, Li CJ, Wu J, Shen N, Xue B. Urinary levels of dimethoate, bisphenol A and benzo[a]pyrene in first-year students of Hohai University from different geographical regions. BMC Public Health. 2021 Sep 16;21(1):1692. doi: 10.1186/s12889-021-11726-4. PMID: 34530795 Free PMC article.

26. Zhang Q, Shen J, Wu Y, Ruan W, Zhu F, Duan S. LINC00520: A Potential Diagnostic and Prognostic Biomarker in Cancer. Front Immunol. 2022 Mar 2;13:845418. doi: 10.3389/fimmu.2022.845418. eCollection 2022. PMID: 35309319 Free PMC article. Review.

27. Xu F, Zhu F, Wang W, Gao W, Chen X, Yu C.Down-regulation of miRNA-196b expression inhibits the proliferation, migration and invasiveness of HepG2 cells while promoting their apoptosis via the PI3K/Akt signaling pathway. Cell Mol Biol (Noisy-le-grand). 2020 Jun 5;66(3):159-164. PMID: 32538764

28. Cheng Q, Yuan X, Lin S, Zhao Y, Wang H, Zhu F, Wang Y, Xu T, Wu J, Wang K, Zhang J, Sun X, Li C, Liang H, Fang L, Xue B. Serum proteome profiling reveals differentially expressed proteins between subjects with metabolically healthy obesity and nonalcoholic fatty liver disease. J Proteomics. 2022 Mar 11;260:104556. doi: 10.1016/j.jprot.2022.104556. Online ahead of print. PMID: 35283354

29. Cheng F, Du L, Kim JJ, Zhu F, He H, Dai N. NMDA and AMPA receptor physiology and role in visceral hypersensitivity: a review. Eur J Gastroenterol Hepatol. 2022 Mar 29:MEG.0000000000002351. doi: 10.1097/MEG.0000000000002351. Online ahead of print. PMID: 35352689

30. Zou M, Shen J, Wu Y, Zhong C, Fang L, Zhu F, Duan S. Dysregulation of miR-411 in cancer: Causative factor for pathogenesis, diagnosis and prognosis. Biomed Pharmacother. 2022 Mar 28;149:112896. doi: 10.1016/j.biopha.2022.112896. Online ahead of print.

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