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姓名: 刘瑞霞
职称: 副研究员
单位: 首都医科大学附属北京友谊医院 感染内科
简历介绍:

女,医学博士,副研究员。主要从事急性胰腺炎、肝纤维化的基础和临床研究工作。作为课题第一责任人,承担国家自然科学基金青年基金、中国博士后特殊资助项目、中国博士后面上项目、北京市博士后科学基金、中国肝炎基金会-王宝恩肝纤维化基金各一项;参与国家自然科学基金、北京市自然科学基金、首都特色项目等多项课题研究。2012至2016年间发表SCI收录期刊论文10篇,其中第一作者6篇;关于急性胰腺炎的研究发表在国际胰腺研究领域较高水平的Pancreas和Pancreatology杂志上。以第一作者在“中华胰腺病杂志”等中文核心期刊杂志发表论文13篇,参与发表论文30余篇。参编著作5部。

主要科研成果:

[1] Jing Wang, Ruixia Liu(共同一作), Haiyu Qi, Yan Wang, Lijian Cui, Yan Wen, Huihui Li, Chenghong Yin. The ACE2-angiotensin-(1-7)-Mas axis protects against pancreatic cell damage in cell culture, Pancreas, 2015, 44(2): 266-272.

[2] Ruixia Liu, Haiyu Qi, Jing Wang, Yan Wang, Lijian Cui, Yan Wen, Chenghong Yin. Angiotensin-converting enzyme (ACE and ACE2) imbalance correlates with the severity of cerulein-induced acute pancreatitis in mice, Exp Physiol, 2014. 99(4): 651-663.

[3] Ruixia Liu, Haiyu Qi, Jing Wang, Yan Wang, Lijian Cui, Yan Wen, Chenghong Yin, Ulinastatin activates the renin- angiotensin system to ameliorate the pathophysiology of severe acute pancreatitis, J Gastroenterol Hepatol, 2014. 29(6):1328-1337.

[4] Ruixia Liu, Yuanyuan Wang, Ying Xiao, Mingjun Shi, Guozhong Zhang, Bing Guo, SnoN as a Key Regulator of the High Glucose-Induced Epithelial-Mesenchymal Transition in Cells of the Proximal Tubule, Kidney Blood Press Res, 2012, 35(6):517-528.

[5] Liu Xiaoya, Liu Ruixia(共同一作), Hou Fei, Cui Lijia, Wen Yan, Yin Chenghong. Fibronectin expression is critical for liver fibrogenesis in vivo and in vitro. Mol Med Rep, 2016 (Accept)

[6] Hou Fei, Liu Ruixia(共同一作), Liu Xiaoya, Cui Lijia, Xiaozheng Yu, Wen Yan, Ding Huiguo, Yin Chenghong. Decreased levels of Arkadia protein expression in the liver during the progression of hepatic fibrosis. Int J Mol Med, 2016 (Accept).

[7] Hou F, Liu RX, Liu XY, Cui LJ, Wen Y, Yan SB, Yin CH. Attenuation of Liver Fibrosis by Herbal Compound 861 through Upregulating of BMP-7/Smad Signaling in Bile Duct Ligation Rat. Mol Med Rep, 2016, 13(5):4335-4342.

[8] Xiuji Li, Zongli Diao, Jiaxiang Ding, Ruixia Liu, Liyan Wang, Wen Huang, Wenhu Liu. The downregulation of SnoN expression in human renal proximal tubule epithelial cells under high-glucose conditions is mediated by an increase in Smurf2 expression through TGF-β1 signaling, Int J Mol Med, 2016, 37(2):415-422.

[9] Entong Yi, Ruixia Liu, Yan Wen, Chenghong Yin. Telmisartan attenuates hepatic fibrosis in bile duct-ligated rats, Acta Pharmacologica Sinica, 2012, 33(12):1518-1524.

[10] Yan Wang, Jing Wang, Ruixia Liu, Haiyu Qi, Yan Wen, Fangfang Sun, Chenghong Yin. Severe acute pancreatitis is associated with upregulation of the ACE2-angiotensin-(1-7)-Mas axis and promotes increased circulating angiotensin-(1-7), Pancreatology, 2012, 12(5):451-457.

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