医学博士，博士生导师，中华医学会肝病学会青委，广东省感染病分会青委副主委，曾赴新加坡和德国访问学习，主持和参与多项国家级课题，发表SCI论文10余篇，曾经获得广东省科技进步一等奖和中华医学科技二等奖。主要从事慢性HBV感染及肝癌免疫调节机制的研究。

已发表论文：

1.Tang LB, Chen CC, Gao XP, Zhang WY, Yan X, Zhou Y, Guo L, Zheng XC, Wang WB, Yang FQ, Liu GZ, Sun J, Hou JL, Li YY. Interleukin-21 Reinvigorates the Antiviral Activity of Hepatitis B Virus (HBV)-Specific CD8+ T Cells in Chronic HBV Infection. J Infect Dis. 2019; 219(5):750-759.) (Corresponding author, IF: 5.2)

2.Zheng XC, Zhou Y, Yi X, Chen CC, Wen CH, Ye GF, Li XY, Tang LB, Zhang XY, Yang FQ, Liu GZ, Li YY and Hou JL. IL-21 Receptor Signaling Is Essential for Control of Hepatocellular Carcinoma Growth and Immunological Memory for Tumor Challenge. OncoImmunology. OncoImmunology. 2018 Sep 26;7(12):e1500673. (Corresponding author, IF: 5.5)

3.Tang LB, Zhong RH, He XQ, Wang WB, Liu JH, Zhu YF, Li YY, Hou JL. Evidence for the association between IgG-antimitochondrial antibody and biochemical response to ursodeoxycholic acid treatment in primary biliary cholangitis. J Gastroenterol Hepatol. 2017;32(3):659-666. (Co-corresponding author, IF: 3.32)

4.Li YY, Wang WB, Tang LB, He XQ, Yan X, Zhang XY, Zhu YF, Sun J, Shi YQ,Ma X, Ian R. Mackay, M. Eric Gershwin, Han Y, Hou JL. CXCL13 Promotes Intrahepatic CXCR5+ Lymphocyte Homing and Aberrant B cell Immune Responses in Primary Biliary Cirrhosis. Hepatology. 2015; 61(6):1998-2007.  (First author, IF: 11.19)

5.Li YY, Tang LB, Hou JL. Role of interleukin-21 in HBV infection: friend or foe? Cell Mol Immunol. 2015; 12(3):303-8. (First author, IF: 4.19)

主持课题：

1、国自然面上项目：“滤泡辅助性T 细胞-IL21-B 细胞”轴参与慢性HBV 感染HBsAg 血清学转换的免疫机制研究

2、国自然青年项目：利用T 细胞受体样抗体研究NK 细胞ADCC 效应在慢性HBV 感染中的作用