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慢性HBV感染者血脂和白蛋白-胆红素指数与疾病进展的关系

曹雯君 王同同 郜玉峰 邹桂舟

引用本文:
Citation:

慢性HBV感染者血脂和白蛋白-胆红素指数与疾病进展的关系

DOI: 10.3969/j.issn.1001-5256.2019.03.014
基金项目: 

安徽省自然科学基金(1608085MH164); 

详细信息
  • 中图分类号: R512.62;R575

Association of blood lipids and albumin-bilirubin index with disease progression in patients with chronic hepatitis B virus infection

Research funding: 

 

  • 摘要: 目的探讨血脂相关指标及白蛋白-胆红素指数(ALBI指数)对慢性HBV感染后疾病进展的评估价值。方法选取2016年6月-2017年6月在安徽医科大学第二附属医院就诊的184例慢性HBV感染者,将其根据不同的疾病阶段分为HBV携带者74例(ASC组),慢性乙型肝炎患者70例(CHB组),代偿期肝硬化患者40例(LC组),并以50例健康对照者作为对照(HC组)。检测血脂相关指标和肝功能指标,分析血脂指标与ALBI指数在慢性HBV感染后疾病进展中的变化特点。计量资料多组间比较采用单因素方差分析,进一步两两比较采用Dunnett法;计数资料组间比较采用χ2检验;相关性分析采用Pearson相关分析法。结果 ASC组、CHB组、LC组、HC组间血脂指标CHO、HDL-C、LDL-C、APOA、APOB差异均有统计学意义(F值分别为12. 075、19. 559、6. 554、9. 392、5. 458,P值均<0. 001);与其他3组比较,LC组以上指标降低最为显著,组间差异均有统计学意义(P值均<0. 05)。ALBI指数在4组间差异有统计学意义(F=49. 225,P <0...

     

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  • 收稿日期:  2018-10-09
  • 出版日期:  2019-03-20
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