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FibroScan对慢性丙型肝炎进展期肝纤维化的诊断价值及其影响因素

仇丽霞 梁珊 范作鹏 马丽霞 韦新焕 郭海清 林伟 刘义荣 于海滨 柳雅立 张晶

仇丽霞, 梁珊, 范作鹏, 马丽霞, 韦新焕, 郭海清, 林伟, 刘义荣, 于海滨, 柳雅立, 张晶. FibroScan对慢性丙型肝炎进展期肝纤维化的诊断价值及其影响因素[J]. 临床肝胆病杂志, 2019, 35(9): 1950-1953. DOI: 10.3969/j.issn.1001-5256.2019.09.013.
引用本文: 仇丽霞, 梁珊, 范作鹏, 马丽霞, 韦新焕, 郭海清, 林伟, 刘义荣, 于海滨, 柳雅立, 张晶. FibroScan对慢性丙型肝炎进展期肝纤维化的诊断价值及其影响因素[J]. 临床肝胆病杂志, 2019, 35(9): 1950-1953. DOI: 10.3969/j.issn.1001-5256.2019.09.013.
Chou LiXia, Liang Shan, Fan ZuoPeng, Ma LiXia, Wei XinHuan, Guo HaiQing, Lin Wei, Liu YiRong, Yu HaiBin, Liu YaLi, Zhang Jing. Value of FibroScan in the diagnosis of progressive liver fibrosis in patients with chronic hepatitis C and related influencing factors[J]. J Clin Hepatol, 2019, 35(9): 1950-1953. DOI: 10.3969/j.issn.1001-5256.2019.09.013.
Citation: Chou LiXia, Liang Shan, Fan ZuoPeng, Ma LiXia, Wei XinHuan, Guo HaiQing, Lin Wei, Liu YiRong, Yu HaiBin, Liu YaLi, Zhang Jing. Value of FibroScan in the diagnosis of progressive liver fibrosis in patients with chronic hepatitis C and related influencing factors[J]. J Clin Hepatol, 2019, 35(9): 1950-1953. DOI: 10.3969/j.issn.1001-5256.2019.09.013.

FibroScan对慢性丙型肝炎进展期肝纤维化的诊断价值及其影响因素

DOI: 10.3969/j.issn.1001-5256.2019.09.013
基金项目: 

首都医学大学附属北京佑安医院院内中青年人才孵育项目(YNKTTS20180114); 

详细信息
  • 中图分类号: R512.63

Value of FibroScan in the diagnosis of progressive liver fibrosis in patients with chronic hepatitis C and related influencing factors

Research funding: 

 

  • 摘要: 目的分析FibroScan对慢性丙型肝炎进展期肝纤维化的诊断效能并探讨其影响因素。方法选取2015年6月-2018年6月于首都医科大学附属北京佑安医院就诊的慢性丙型肝炎患者,均完成肝穿刺病理检查。根据METAVIR评分系统进行纤维化分期,分为F1~F4期。收集患者一般资料,所有患者进行肝脏弹性检测和肝功能、血常规、病毒定量等检测,利用公式计算APRI及FIB-4。不符合正态分布的计量资料多组间比较采用Kruskal-Wallis H秩和检验,进一步两两比较采用Wilcoxon秩和检验。相关性检验采用Spearman秩相关分析。利用受试者工作特征曲线(ROC曲线)分析3种无创诊断方法对肝纤维化的诊断价值,采用STATA验证3种无创诊断方法是否存在统计学差异。结果入组患者共131例,其中男60例(45. 80%),女71例(54. 20%),平均54. 00(45. 00~58. 25)岁。FibroScan水平为7. 80(5. 60~14. 30) kPa,APRI水平为0. 63(0. 37~1. 28),FIB-4水平为2. 28(1. 43~3. 60)。随着肝纤维化分期的进展,...

     

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  • 收稿日期:  2019-05-07
  • 出版日期:  2019-09-20
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