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Epidemiology of nonalcoholic fatty liver disease in some regions of China
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摘要:
非酒精性脂肪性肝病(NAFLD)已经取代病毒性肝炎成为全球第一大慢性肝病。国内目前诊断NAFLD仍以腹部B超为主要手段。过去20年内,国内研究显示人群的NAFLD患病率为13%～43%,且NAFLD患病率呈逐年上升趋势,每年新发NAFLD的人数比例约为4%,其中非肥胖NAFLD也有一定的患病率。不同区域人群患病率存在显著差异,经济水平更为发达、居民生活习惯更接近西方社会生活习惯的东南沿海地区,NAFLD患病率更高。2型糖尿病、肥胖症、高脂血症、高尿酸血症、高血压等代谢异常疾病是NAFLD患病的危险因素。我国仍然需要更严谨更大样本的大范围流行病学调查来明确NAFLD的患病因素,以及进一步加大对NAFLD的诊治和预防的宣传力度。
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关键词:
- 非酒精性脂肪肝性肝病 /
- 患病率 /
- 发病率 /
- 代谢疾病
Abstract:Nonalcoholic fatty liver disease( NAFLD) has replaced viral hepatitis and become the most important chronic liver disease in the world. Abdominal ultrasound remains the main method for the diagnosis of NAFLD in China. The studies in China showed that in the last two decades,the prevalence rate of NAFLD was 13%-43% and tended to increase year by year,and the new cases accounted for about 4%each year,with a certain proportion of patients with non-obese NAFLD. There is a significant difference in prevalence rate between the populations from different regions,with a higher prevalence rate of NAFLD in the well-developed southeast coastal regions where people have a similar lifestyle to those in Western countries. Metabolic disorders,such as type 2 diabetes,obesity,hyperlipidemia,hyperuricemia,and hypertension,are risk factors for NAFLD. National-wide large-sample epidemiological investigation is still needed in China to help support the diagnosis,treatment,and prevention of NAFLD.
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Key words:
- non-alcoholic fatty liver disease /
- prevalence /
- incidence /
- metabolic diseases
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