Recently, the International Association of Pancreatology published a revised edition of the guidelines for the management of intraductal papillary mucinous neoplasm (IPMN) of the pancreas. The guidelines mainly focus on five topics, i.e., revision of “high-risk stigmata” and “worrisome features”, surveillance of unresected IPMN, surveillance after resection of IPMN, revision of pathological aspects, and research on molecular markers in cyst fluid, in order to provide the best evidence-based reference for clinical practice. This article makes an excerpt of the key points in the guidelines.