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Volume 40 Issue 8
Aug.  2024
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Article Navigation >  Journal of Clinical Hepatology  > 2024  >  40(8): 1688-1692

Association of lipid metabolism reprogramming with the development and progression of primary liver cancer

DOI: 10.12449/JCH240829
  • 1.

    Graduate School，Guangxi University of Chinese Medicine，Nanning 530200，China

  • 2a.

    Department of Scientific Research，The First Affiliated Hospital of Guangxi University of Chinese Medicine Nanning 530023，China

  • 2b.

    Department of Hepatology，The First Affiliated Hospital of Guangxi University of Chinese Medicine，Nanning 530023，China

Research funding:

National Natural Science Foundation of China (82274434);

National Natural Science Foundation of China (81960841);

National Natural Science Foundation of China (82060848);

Guangxi Natural Science Foundation (2020GXNSFBA297115);

Guangxi Natural Science Foundation (2020GXNSFAA297070);

Doctoral Start-up Fund of Guangxi University of Chinese Medicine (2020BS026);

The First Affiliated Hospital of Guangxi University of Chinese Medicine Doctoral Start-up Fund (2020BS003);

Innovation Project of Guangxi Graduate Education (YCSW2023378);

Innovation Project of Guangxi Graduate Education (YCBZ2023157);

Innovation Project of Guangxi Graduate Education (YCSW2023384);

Innovation Project of Guangxi Graduate Education of GXUCM (YCSY2022024);

Project on Enhancement of Basic Research Ability of Young and Middle-aged Teachers in Guangxi Universities and Colleges (2022KY0284);

Project on Enhancement of Basic Research Ability of Young and Middle-aged Teachers in Guangxi Universities and Colleges (2023KY0324)

More Information
  • Corresponding author: WANG Minggang， wmgyx2012@163.com （ORCID： 0000-0002-2781-6777）
  • Received Date: 2023-09-28
  • Accepted Date: 2023-11-08
  • Published Date: 2024-08-25
    Abstract
  • Lipid metabolism， as the basis of life maintenance， is a prerequisite for cell survival， and lipid homeostasis can rapidly respond to metabolic changes in a coordinated manner. In cancers， there is an increase in lipid metabolism in cancer cells to meet the requirements for plasma membrane synthesis and energy production. Abnormal lipid metabolism plays an important role in the progression of primary liver cancer. This article reviews the association between abnormal lipid metabolism and primary liver cancer， in order to find targets for the prevention and treatment of primary liver cancer.

     

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