The American College Gastroenterology (ACG) recently released the 2024 edition of Guidelines for the management of acute pancreatitis. The guidelines first discuss the diagnosis, etiology, severity, and early management of acute pancreatitis, as well as the management of complications, especially pancreatic necrosis, and then the guidelines propose the clinical decisions such as antibiotics, nutrition, endoscopy, radiology, and surgical intervention. This article makes an excerpt of the key concepts and recommendations in the guidelines.