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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 40 Issue 10
Oct.  2024
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Article Contents

Therapeutic paradigms and potential therapies for nonalcoholic steatohepatitis

DOI: 10.12449/JCH241025
Research funding:

Jilin Provincial Department of Science and Technology Project (20210401054YY)

More Information
  • Corresponding author: LI Feng, 18943994025@163.com (ORCID: 0009-0009-8760-3675)
  • Received Date: 2024-02-21
  • Accepted Date: 2024-03-26
  • Published Date: 2024-10-25
  • In recent years, steady progress has been made in the epidemiology, pathogenesis, and therapeutic targets of nonalcoholic steatohepatitis (NASH), while there has been slow progress in the field of therapeutic drug development. This article reviews the advances in lifestyle intervention, surgical methods, gut microbiota, and drugs in the treatment of NASH, especially the role of insulin sensitizers, antioxidants, cholesterol-lowering drugs, thyroid hormone mimetics, incretins, and cytokines in the treatment of NASH, in order to provide more methods and options for the treatment of NASH in the future.

     

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