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Volume 41 Issue 1
Jan.  2025
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Article Navigation >  Journal of Clinical Hepatology  > 2025  >  41(1): 183-188

Research advances in liver venous deprivation

DOI: 10.12449/JCH250128
  • 1.

    Graduate School，Qinghai University，Xining 810001，China

  • 2.

    Department of Hepatobiliary Surgery，The Affiliated Hospital of Qinghai University，Xining 810001，China

  • 3.

    Department of Hepatobiliary Surgery，The Second Hospital of Shandong University，Jinan 250033，China

  • 4.

    Hepato-pancreato-biliary Center，Beijing Tsinghua Changgung Hospital，School of Clinical Medicine，Tsinghua University，Beijing 102218，China

Research funding:

National Natural Science Foundation of China (82027807);

National Natural Science Foundation of China (81930119)

More Information
  • Corresponding author: XIANG Canhong， roy.xx@163.com （ORCID： 0000-0002-2316-5778）
  • Received Date: 2024-04-11
  • Accepted Date: 2024-05-16
  • Published Date: 2025-01-25
    Abstract
  • Portal vein embolization （PVE） can induce atrophy of the embolized lobe and compensatory regeneration of the non-embolized lobe. However， due to inadequate regeneration of future liver remnant （FLR） after PVE， some patients remain unsuitable for hepatectomy after PVE. In recent years， liver venous deprivation （LVD）， which combines PVE with hepatic vein embolization （HVE）， has induced enhanced FLR regeneration. Compared with associating liver partition and portal vein ligation for staged hepatectomy （ALPPS）， LVD triggers faster and more robust FLR regeneration， with lower incidence rate of postoperative complications and mortality rate. By reviewing related articles on LVD， this article introduces the effectiveness of LVD and analyzes the differences and safety of various technical paths， and it is believed that LVD is a safe and effective preoperative pretreatment method.

     

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