[1] MILLER CS.Pleiotropic mechanisms of virus survival and persistence[J].Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2005, 100 (2Suppl) :s27-s36.
|
[2] VIVIER E, TOMASELLO E, BARATIN M, et al.Functions of natural killer cells[J].Nat Immunol, 2008, 9 (5) :503-510.
|
[3]CALIGIURI MA.Human natural killer cells[J].Blood, 2008, 112 (3) :461-469.
|
[4]AHLENSTIEL G.The natural killer cell response to HCV infection[J].Immune Netw, 2013, 13 (5) :168-176.
|
[5] OLIVIERO B, VARCHETTA S, PAUDICE E, et al.Natural killer cell functional dichotomy in chronic hepatitis B and chronic hepatitis C virus infections[J].Gastroenterology, 2009, 137 (3) :1151-1160.
|
[6] MONDELLI MU, VARCHETTA S, OLIVIERO B.Natural killer cells in viral hepatitis:facts and controversies[J].Eur J Clin Invest, 2010, 40 (9) :851-863.
|
[7]MAINI MK, PEPPA D.NK cells:a double-edged sword in chronic hepatitis B virus infection[J].Front Immunol, 2013, 4:57.
|
[8]BUSCA A, KUMAR A.Innate immune responses in hepatitis B virus (HBV) infection[J].Virol J, 2014, 11:22.
|
[9] van der MOLEN RG, SPRENGERS D, BINDA RS, et al.Functional impairment of myeloid and plasmacytoid dendritic cells of patients with chronic hepatitis B[J].Hepatology, 2004, 40 (3) :738-746.
|
[10] KANTO T, INOUE M, MIYATAKE H, et al.Reduced numbers and impaired ability of myeloid and plasmacytoid dendritic cells to polarize T helper cells in chronic hepatitis C virus infection[J].J Infect Dis, 2004, 190 (11) :1919-1926.
|
[11] OP den BROUWML, BINDA RS, van ROOSMALEN MH, et al.Hepatitis B virus surface antigen impairs myeloid dendritic cell function:a possible immune escape mechanism of hepatitis B virus[J].Immunology, 2009, 126 (2) :280-289.
|
[12]SHI B, REN G, HU Y, et al.HBsAg inhibits IFN-alpha production in plasmacytoid dendritic cells through TNF-alpha and IL-10induction in monocytes[J].PLoS One, 2012, 7 (9) :e44900.
|
[13]KRISHNADAS DK, AHN JS, HAN J, et al.Immunomodulation by hepatitis C virus-derived proteins:targeting human dendritic cells by multiple mechanisms[J].Int Immunol, 2010, 22 (6) :491-502.
|
[14]ZHAO L, TYRRELL DL.Myeloid dendritic cells can kill T cells during chronic hepatitis C virus infection[J].Viral Immunol, 2013, 26 (1) :25-39.
|
[15] LI L, LIU M, CHENG LW, et al.HBcAg-specific IL-21-producing CD4+T cells are associated with relative viral control in patients with chronic hepatitis B[J].Scand J Immunol, 2013, 78 (5) :439-446.
|
[16] FENG G, ZHANG JY, ZENG QL, et al.HCV-specific interleukin-21+CD4+T cells responses associated with viral control through the modulation of HCV-specific CD8+T cells function in chronic hepatitis C patients[J].Mol Cells, 2013, 36 (4) :362-367.
|
[17] STOOP JN, van der MOLEN RG, BAAN CC, et al.Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection[J].Hepatology, 2005, 41 (4) :771-778.
|
[18] CABRERA R, TU Z, XU Y, et al.An immunomodulatory role for CD4 (+) CD25 (+) regulatory T lymphocytes in hepatitis C virus infection[J].Hepatology, 2004, 40 (5) :1062-1071.
|
[19] BELKAID Y, TARBELL K.Regulatory T cells in the control of host-microorganism interactions[J].Annu Rev Immunol, 2009, 27:551-589.
|
[20]BELKAID Y, ROUSE BT.Natural regulatory T cells in infectious disease[J].Nat Immunol, 2005, 6 (4) :353-360.
|
[21]MOORMAN JP, WANG JM, ZHANG Y, et al.Tim-3 pathway controls regulatory and effector T cell balance during hepatitis C virus infection[J].J Immunol, 2012, 189 (2) :755-766.
|
[22]ZHANG Y, MA CJ, NI L, et al.Cross-talk between programmed death-1 and suppressor of cytokine signaling-1 in inhibition of IL-12 production by monocytes/macrophages in hepatitis C virus infection[J].J Immunol, 2011, 186 (5) :3093-3103.
|
[23] ZHANG Y, MA CJ, WANG JM, et al.Tim-3 negatively regulates IL-12 expression by monocytes in HCV infection[J].PLoS One, 2011, 6 (5) :e19664.
|
[24] LARRUBIA JR, LOKHANDE MU, GARCIA-GARZON S, et al.Persistent hepatitis C virus (HCV) infection impairs HCV-specific cytotoxic T cell reactivity through Mcl-1/Bim imbalance due to CD127 down-regulation[J].J Viral Hepat, 2013, 20 (2) :85-94.
|
[25] SEIGEL B, BENGSCH B, LOHMANN V, et al.Factors that determine the antiviral efficacy of HCV-specific CD8 (+) T cells ex vivo[J].Gastroenterology, 2013, 144 (2) :426-436.
|
[26] KROY DC, CIUFFREDA D, COOPERRIDER JH, et al.Liver environment and HCV replication affect human T-Cell phenotype and expression of inhibitory receptors[J].Gastroenterology, 2014, 146 (2) :550-561.
|
[27]PURDY MA.Hepatitis B virus S gene escape mutants[J].Asian J Transfus Sci, 2007, 1 (2) :62-70.
|
[28] EZZIKOURI S, OZAWA M, KOHARA M, et al.Recent insights into hepatitis B virus-host interactions[J].J Med Virol, 2014, 86 (6) :925-932.
|
[29] GE D, FELLAY J, THOMPSON AJ, et al.Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance[J].Nature, 2009, 461 (7262) :399-401.
|
[30] SUPPIAH V, MOLDOVAN M, AHLENSTIEL G, et al.IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy[J].Nat Genet, 2009, 41 (10) :1100-1104.
|
[31] TANAKA Y, NISHIDA N, SUGIYAMA M, et al.Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C[J].Nat Genet, 2009, 41 (10) :1105-1109.
|
[32] THOMAS DL, THIO CL, MARTIN MP, et al.Genetic variation in IL28B and spontaneous clearance of hepatitis C virus[J].Nature, 2009, 461 (7265) :798-801.
|
[33] BODE JG, BRENNDORFER ED, HUSSINGER D.Subversion of innate host antiviral strategies by the hepatitis C virus[J].Arch Biochem Biophys, 2007, 462 (2) :254-265.
|
[34] SERRE SB, KRARUP HB, BUKH J, et al.Identification of IFNalpha induced envelope mutations of hepatitis C virus in vitro associated with increased viral fitness and interferon resistance[J].J Virol, 2013, 87 (23) :12776-12793.
|
[35]LI XD, SUN L, SETH RB, et al.Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity[J].Proc Natl Acad Sci U S A, 2005, 102 (49) :17717-17722.
|
[36]LI K, FOY E, FERREON JC, et al.Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF[J].Proc Natl Acad Sci U S A, 2005, 102 (8) :2992-2997.
|
[37]DING Q, CAO X, LU J.et al.Hepatitis C virus NS4B blocks the interaction of STING and TBK1 to evade host innate immunity[J].J Hepatol, 2013, 59 (1) :52-58.引证本文:ZHOU Y, LIAN JQ, JIA ZS.Persistent hepatitis virus infection and immune homeostasis[J].J Clin Hepatol, 2014, 30 (9) :851-854. (in Chinese) 周云, 连建奇, 贾战生.持续性HBV或HCV感染与免疫稳态[J].临床肝胆病杂志, 2014, 30 (9) :851-854.
|