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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 9
Sep.  2014
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Article Contents

Research progress in TIM-3 and HBV infection

DOI: 10.3969/j.issn.1001-5256.2014.09.025
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  • Received Date: 2013-11-19
  • Published Date: 2014-09-20
  • Studies have found that T cell Ig- and mucin- domain- containing molecule- 3 ( TIM- 3) is associated with the development of many diseases. In hepatitis B virus ( HBV) infection, TIM- 3 acts as a negative immune regulatory molecule and its expression on CD8+T cells increases markedly. It indicates that TIM- 3 is closely related to the pathogenic mechanism of HBV infection. The latest research progress in TIM- 3 and HBV infection, including the biological characteristics of TIM- 3 and the outcomes and new therapeutic target of HBV infection, is reviewed and summarized. It is thought that TIM- 3 will become a new target in the treatment of HBV.

     

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