Hepatitis C virus(HCV) infection is one of the most common causes of chronic hepatitis,liver cirrhosis,and hepatocellular carcinoma.Micro RNAs(mi RNAs),a class of small,non-coding RNA,are involved in a variety of physiological and pathological processes in human bodies.The mechanism by which miRNAs regulate HCV replication is described,and the effects of liver-specific micro RNA-122 antagonists on hepatitis C antiviral therapy are discussed.Our study indicates that miRNAs play an important regulatory role in HCV expression.Targeting miRNAs may be a potential therapeutic approach for treating HCV infection,but further studies are still in need.
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