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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 8
Aug.  2016
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Article Contents

Research advances in liver cirrhosis complicated by portal vein thrombosis

DOI: 10.3969/j.issn.1001-5256.2016.08.042
  • Received Date: 2016-02-29
  • Published Date: 2016-08-20
  • Portal vein thrombosis( PVT) is a common complication in patients with liver cirrhosis. The development of PVT in patients with liver cirrhosis has not been taken seriously emphasis by clinicians,and there are few related studies. Up to now,no consensus has been reached on the diagnosis and treatment of liver cirrhosis complicated by PVT. In recent years,with the improvement in clinical diagnosis and treatment techniques and increasing knowledge of this disease,the influence of PVT on the course of disease in patients with liver cirrhosis has been taken seriously. This article investigates the development and progression,diagnosis,prevention,and related therapeutic methods of PVT in patients with liver cirrhosis.

     

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  • [1]CHEN H,HE CY,HAN GH,et al.Portal vein thrombosis in liver cirrhosis prevention and treatment progress[J].Chin J Dig,2014,34(1):7-10.(in Chinese)陈辉,何创业,韩国宏,等.肝硬化门静脉血栓预防和治疗进展[J].中华消化杂志,2014,34(1):7-10.
    [2] DAS SK,RAY A,JANA CK,et al.Chronic portal vein thrombosis due to combined deficiency of protein and protein S[J].J Indian Med Assoc,2011,109(10):753-754.
    [3]FRANCOZ C,VALLA D,DURAND F.Portal vein thrombosis,cirrhosis,and liver transplantation[J].Hepatol,2012,57(1):203-212.
    [4]QI X,BAI M,YANG Z,et al.Occlusive portal vein thrombosis as a new marker of decompensaed cirrhosis[J].Med Hypotheses,2011,76(4):522-526.
    [5]GIRLEANU I,STANCIU C,COJOCARIU C,et al.Natural course of nonmalignant partial portal vein thrombosis in cirrhotic patients[J].Saudi J Gastroenterol,2014,20(5):288-292.
    [6]KINJO N,KAWANAKA H,AKAHOSHI T,et al.Portal vein thrombosis in liver cirrhosis[J].World J Hepatol,2014,6(2):64-71.
    [7]BAS SA,STONE CD,GISH R.Portal vein thrombosis[J].Clin Liver Dis,2010,19(1):199-221.
    [8]TSOCHATZIS WA,SENZOLO M,GERMANI G,et al.Systematic review:portal vein thrombosis in cihosis[J].Aliment Pharmacol T-her,2010,31(3):366-374.
    [9] HOEKSTRA J,JANSSEN HL.Vascular liver disorders(Ⅱ):portal vein thrombosis[J].Neth J Med,2009,67(2):46-53.
    [10]TRIPODI A,PRIMIGNANI M,CHANTARANGKUL V,et al.An imbalance of pro-vs anti-coagulation factors in plasma from patients with cirrhosis[J].Gastroenterology,2009,137(6):2105-2111.
    [11] SENZOLO M.Liver:PVT in cirrhosis,not always an innocent bystander[J].Nat Rev Gastroenterol Hepatol,2015,12(1):11-13.
    [12]ZHENG S,YAN XH,LIU H,et al.Analysis of the risk factors of portal veinthrombosis in liver cirrhosis patients[J].Chin Hepatol,2009,14(6):446-448.(in Chinese)郑盛,严晓会,刘海,等.肝硬化患者门静脉血栓形成危险因素的Logistic回归分析[J].肝脏,2009,14(6):446-448.
    [13]HAN JB,YI YX,DING H,et al.Preoperative risk factors of portal venous thrombosis after splenectomy and gastric pericardial devascularization for portal hypertension[J].Chin J Hepatol,2014,22(10):739-743.(in Chinese)韩建波,易永祥,丁海,等.门静脉高压症脾切断流术后门静脉血栓的术前相关危险因素分析[J].中华肝脏病杂志,2014,22(10):739-743.
    [14]NERY F,CHEVRET S,CONDAT B,et al.Causes and consequences of portal vein thrombosis in 1243 patients with cirrhosis:results of a longitudinal study[J].Hepatology,2015,61(2):660-667.
    [15] SAUGEL B,LEE M,FEICHTINGER S,et al.Thrombophilic factr anslysis in cirrhosis patients with portal vein thrombosis[J].Thromb Thrombolysis,2015,40(1):54-60.
    [16]KAWANAKA H,AKAHOSHI T,ITOH S,et al.Optimizing risk stratification in portal vein thrombosis after splenectomy and its primary prophylaxis with antithrombin III concentrates and danaparoid sodium in liver cirrhosis with portal hypertension[J].J Am Coll Surg,2014,219(5):865-874.
    [17]ZANG LN,XING HH,WANG JH,et al.Progress in portal vein thrombosis in patients with liver cirrhosis[J].J Pract Hepatol,2014,17(4):429-432.(in Chinese)臧立娜,邢慧慧,王嘉菲,等.肝硬化并发门静脉血栓研究进展[J].实用肝脏病杂志,2014,17(4):429-432.
    [18] QI X,HAN G,BAI M,et al.Stage of portal vein thrombosis[J].J Hepatol,2011,54(1):78-88.
    [19]DELEVE LD,VALLA DC,GARCIA-TSAO G.Vascular disorders of the liver[J].Hepatology,2009,49(5):1729-1764.
    [20]PONZIANI FR,ZOCCO MA,CAMPANALE C,et al.Portal vein thrombosis insight into physiopathology,diagnosis,and treatment[J].World J Gastroenterol,2010,16(2):143-155.
    [21]QI XS,BAI M,FAN DM.Nonselectiveβ-blockers may induce developement of portal vein thrombosis incirrhosis[J].World J Gastroenterol,2014,20(32):11463-11466.
    [22] ALONSO-COELLO P,BELLMUNT S,McG ORRIAN C,et al.Antithrombotic therapy in peripheral artery disease:antithrombotic therapy and prevention of thrombosis,9th ed:American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.[J].Chest,2012,141(2 Suppl):e669s-e690s.
    [23]NAESHIRO N,AIKATA H,HYOGO H,et al.Efficacy and safety of the anticoagulant drug,danaproid sodium,in the treatment of portal vein thrombosis in patients with liver cirrhosis[J].Hepatol Res,2015,45(6):656-662.
    [24]AMITRANO L,GUARDASCIONE MA,MENCHISE A,et al.Safety and efficacy of anticoagulation therapy with low molecular weight heparin for portal vein thrombosis in patients with liver cirrhosis[J].J Clin Gastroenterol,2010,44(6):448-451.
    [25] DELGADO MG,SEIJO S,YEPES I,et al.Efficacy and safety of anticoagulation on patients with cirrhosis and portal vein thrombosis[J].JClin Gastroenterol,2010,44(6):448-451.
    [26]LISMAN T,KAMPHUISEN PW,NORTHUP PG,et al.Established and new generation antithrombotic drugs in patients with cirrhosis possibilities and caveats[J].J Hepatol,2013,59(2):358-366.
    [27] HAN YL,SHI XB.Antithrombotic and thrombolytic therapy:basis and practice[M].Beijing:People’s Military Medical Press,2014:204-206.(in Chinese)韩雅玲,史旭波.抗栓与溶栓治疗-基础与实践[M].北京:人民军医出版社,2014:204-206.
    [28]LENZ K,DIEPLINGER B,BUDER R,et al.Successful treatment of partial portal vein thrombosis(PVT)with low dose rivaroxaban[J].Z Gastroenterol,2014,52(10):1175-1177.
    [29] WANG Z,ZHAO H,WANG X,et al.Clinical outcome comparison between TIPS and EBL in patients with cirrhosis and portal vein thrombosis[J].Abdom Image,2015,40(6):1813-1820.
    [30]HAN GH,MENG XJ,YIN ZX,et al.Transjugular intrahepatic portosystemie shunt and combination with percutaneous transhepatic or transsplenic approach for the treatment of portal vein thrombosis with or without cavernomatous transformation[J].Nat Med J China,2009,89(22):1549-1552.(in Chinese)韩国宏,孟祥杰,殷占新,等.经颈内静脉肝内门腔分流术及联合经皮肝/脾穿刺途径治疗门静脉血栓和(或)海绵样变性[J].中国医学杂志,2009,89(22):1549-1552.
    [31] WANG Z,JIANG MS,ZHANG HL,et al.Is post-TIPS anticoagulation therapy necessary in patients with cirrhosis and portal vein thrombosis?A randomized controlled trial[J].Radiology,2016,279(3):943-951.
    [32]Group of Gastrointestinal Intervention,Chinese Society of Gastroenterology,Chinese Medical Association.Consensus on transjugular intrahepatic portosystemic shunt for treatment of cirrhotic portal hypertension[J].Chin J Dig,2014,34(1):3-6.(in Chinese)中华医学会消化病学会分会消化介入学组.经颈静脉肝内门体静脉分流术治疗肝硬化门静脉高压共识意见[J].中华消化杂志,2014,34(1):3-6.
    [33] Experts Group from the Ministry of Health Special.Expert consensus on technical specifications of treatment of portal hypertension with esophagogastric variceal bleeding(2013 edition)[J].Chin JDigest Surg,2014,13(6):401-404.(in Chinese)卫生和计划生育委员会卫生公益行业科研专项专家组.门静脉高压症食管胃曲张静脉破裂出血治疗技术规范专家共识(2013版)[J].中华消化外科杂志,2014,13(6):401-404.
    [34]FANG H,YANG ZD,WANG DY,et al.Treatment progress of cirrhosis with portal vein thrombosis[J].Chin J Gastroenterol Hepatol,2015,24(8):1030-1032.(in Chinese)方皓,杨正德,王德宇,等.肝硬化并发门静脉血栓的治疗进展[J].胃肠病学和肝病学杂志,2015,24(8):1030-1032.
    [35] LUCA A,MIRALIA R,CARUSO S,et al.Short-and long-term effects of the transjugular intrahepatic portsystemic shunt on portal vein thrombosis in patients with cirrhosis[J].Gut,2011,60(6):846-852.
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