Primary biliary cholangitis,once named primary biliary cirrhosis,is a chronic cholestatic liver disease characterized by immune-mediated damage of small and medium-sized bile ducts. Recently,with the improvement in the knowledge of this disease and the wide application of new immunological and pathological detection techniques,the gap between China and Western countries in the diagnosis and treatment of PBC has been gradually narrowed,and a series of innovative findings and results have also been achieved. This article reviews these achievements and points out future challenges and possible solutions.
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