中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 6
Jun.  2017
Turn off MathJax
Article Contents

Advances in the diagnosis and treatment of pediatric acute pancreatitis

DOI: 10.3969/j.issn.1001-5256.2017.06.039
  • Received Date: 2017-03-14
  • Published Date: 2017-06-20
  • The incidence rate of acute pancreatitis (AP) has been gradually increasing in recent years, and pediatric AP is often seen in clinical practice. Pediatric AP has complex causes and diverse clinical manifestations, and infants and children cannot clearly explain their discomforts, which makes it more difficult to make an accurate diagnosis and may easily cause misdiagnosis, missed diagnosis, and delayed treatment. A deep understanding of pediatric AP helps to improve the diagnosis and treatment level of this disease. This article reviews the advances in the diagnosis and treatment of pediatric AP, in order to provide guidance to clinical practice.

     

  • loading
  • [1]MORINVILLE VD, BARMADA MM, LOWE ME.Increasing incidence of acute pancreatitis at an American pediatric tertiary care center:is greater awareness among physicians responsible?[J].Pancreas, 2010, 39 (1) :5-8.
    [2]NYDEGGER A, HEINE RG, RANUH R, et al.Changing incidence of acute pancreatitis:10-year experience at the Royal Children's Hospital, Melbourne[J].Gastroenterol Hepatol, 2007, 22 (8) :1313-1316.
    [3]PANT C, DESHPANDE A, OLYAEE M, et al.Epidemiology of acute pancreatitis in hospitalized children in the United States from2000-2009[J].PLo S One, 2014, 9 (5) :e95552.
    [4]PARK A, LATIF SU, SHAH AU, et al.Changing referral trends of acute pancreatitis in children:a 12-year single-center analysis[J].Pediatr Gastroenterol Nutr, 2009, 49 (3) :316-322.
    [5]MA MH, BAI HX, PARK AJ, et al.Risk factors associated with biliary pancreatitis in children[J].Pediatr Gastroenterol Nutr, 2012, 54 (5) :651-656.
    [6]UC A.Death in pediatric intensive care unit:not for children with acute pancreatitis[J].Pediatr Gastroenterol Nutr, 2015, 61 (1) :1-2.
    [7]BAI HX, MA MH, ORABI AI, et al.Novel characterization of drug-associated pancreatitis in children[J].J Pediatr Gastroenterol Nutr, 2011, 53 (4) :423-428.
    [8]WU SB, WANG MC.The expression of receptor interacting protein3 in pancreatic tissue of severe acute pancreatitis mice[J].Clin J Med Offic, 2016, 44 (8) :859-861, 865. (in Chinese) 吴善斌, 王孟春.RIP3蛋白在重症急性胰腺炎小鼠胰腺组织中表达[J].临床军医杂志, 2016, 44 (8) :859-861, 865.
    [9]SALUJA AK, DUDEJA V.Relevance of animal models of pancreatic cancer and pancreatitis to human disease[J].Gastroenterology, 2013, 144 (6) :1194-1198.
    [10]MORINVILLE VD, LOWE ME, AHUJA M, et al.Design and implementation of insppire (International Study Group of Pediatric Pancreatitis:in search for a cure) [J].Pediatr Gastroenterol Nutr, 2014, 59 (3) :360-364.
    [11]LI W, XIE XB, QU F.Clinical signfcance of biochemical indicator in diagnosis of acute pancreatitis[J].Lab Med, 2011, 26 (8) :527-530. (in Chinese) 李武, 谢小兵, 屈飞.生化检测指标在急性胰腺炎诊断中的临床意义[J].检验医学, 2011, 26 (8) :527-530.
    [12]COFFEY MJ, NIGHTINGALE S, OOI CY.Serum lipase as an early predictor of severity in pediatric acute pancreatitis[J].Pediatr Gastroenterol Nutr, 2013, 56 (6) :602-608.
    [13]JIA R, TANG M, QIU L, et al.Increased interleukin-23/17 axis and C-reactive protein areassociated with severity of acute pancreatitis in patients[J].Pancreas, 2015, 44 (2) :321-325.
    [14]ENDO K, WENG H, KITO N, et al.MiR-216a and miR-216b as markers for acute phased pancreatic injury[J].Biomed Res, 2013, 34 (4) :179-88.
    [15]GUPTA S, SHEKHAWAT VP, KAUSHIK GG.D-dimer, a Potential marker for the prediction of severity of acute pancreatitis[J].Clin Lab, 2015, 61 (9) :1187-1189.
    [16]COFFEY MJ, NIGHTINGALE S, OOI CY.Diagnosing acute pancreatitis in children:what is the diagnostic yield and concordance for serum pancreatic enzymes and imaging within 96 h of presentation?[J].Pancreatology, 2014, 14 (4) :251-256.
    [17]CHAO HC, LIN SJ, KONG MS, et al.Sonographic evaluation of the pancreatic duct in normal children and children with pancreatitis[J].Ultrasound Med, 2000, 19 (11) :757-763.
    [18]LAUTZ TB, TURKEL G, RADHAKRISHNAN J, et al.Utilityof the computed tomography severity index (Balthazar score) in children with acute pancreatitis[J].Pediatr Surg, 2012, 47 (6) :1185-1191.
    [19]XIAO B, JIANG ZQ, JIAN SH, et al.Acute necrotizing pancreatitis:MRI manifestations of pancreatic walled-off necrosis[J].Diagn Imag Interv Radiol, 2016, 25 (2) :117-122. (in Chinese) 肖波, 蒋志琼, 蹇顺海, 等.急性坏死性胰腺炎:胰腺包裹性坏死 (WON) 的MRI表现和认识[J].影像诊断与介入放射学, 2016, 25 (2) :117-122.
    [20]RESTREPO R, HAGEROTT HE, KULKARNI S, et al.Acute pancreatitis in pediatric patients:demographics, etiology, and diagnostic imaging[J].AJR Am J Roentgenol, 2016, 206 (3) :632-644.
    [21]MIRTALLO JM, FORBES A, MCCLAVE SA, et al.International consensus guidelines for nutrition therapy in pancreatitis[J].JPEN J Parenter Enteral Nutr.2012, 36 (3) :284-291.
    [22]GONG ST.Enteral nutrition in children with acute pancreatitis[J].J Appl Clin Pediatr, 2009, 24 (7) :485-487. (in Chinese) 龚四堂.小儿急性胰腺炎的肠内营养治疗[J].实用儿科临床杂志, 2009, 24 (7) :485-487.
    [23]ZHUANG RD, MA M, LOU JG, et al.Timing of nasojejunal feeding tube placement and enteral nutrition in children with acute pancreatitis[J].Chin J Contemp Pediatr, 2014, 16 (11) :1086-1090. (in Chinese) 庄睿丹, 马鸣, 楼金玕, 等.儿童急性胰腺炎鼻空肠营养置管及肠内营养时机的探讨[J].中国当代儿科杂志, 2014, 16 (11) :1086-1090.
    [24]THOMPSON DR.Narcotic analgesic effects on the sphincter of Oddi:a review of the data and therapeutic implications in treating pancreatitis[J].Am J Gastroenterol, 2001, 96 (4) :1266-1272.
    [25]SUZUKI M, SAI JK, SHIMIZU T.Acute pancreatitis in children and adolescents[J].World J Gastrointest Pathophysiol, 2014, 5 (4) :416-426.
    [26]NOUIRA F, BEN AHMED Y, SARRAI N, et al.Pancreatic pseudocyst in children:what is the best therapeutic approach?[J].Arch Pediatr, 2011, 8 (11) :1176-1180.
    [27]TEH SH, PHAM TH, LEE A, et al.Pancreatic pseudocyst in children:the impact of management strategies on outcome[J].J Pediatr Surg, 2006, 41 (11) :1889-1893.
    [28]JAZRAWI SF, BARTH BA, SREENARASIMHAIAH J.Efficacy of endoscopic ultrasound-guided drainage of pancreatic pseudocysts in a pediatric population[J].Dig Dis Sci, 2011, 56 (3) :902-908.
    [29]ZHANG Y, ZENG WZ, WANG YX, et al.Effect of continuous blood purification in treatment of patients with severe acute pancreatitis and multiple organ dysfunction syndrome[J].J Clin Hepatol, 2016, 32 (2) :320-323. (in Chinese) 张勇, 曾维政, 王云侠, 等.连续性血液净化治疗重症急性胰腺炎合并多器官功能障碍综合征的效果观察[J].临床肝胆病杂志, 2016, 32 (2) :320-323.
    [30]PEI L, LIU CF.Clinical effect of maintenance hemodiafiltration in treatment of severe acute pancreatitis in children:an analysis of 3cases[J].Chin J Contemp Pediatr, 2014, 16 (1) :77-80. (in Chinese) 裴亮, 刘春风.持续性血液透析滤过治疗儿童重症急性胰腺炎3例临床分析[J].中国当代儿科杂志, 2014, 16 (1) :77-80.
    [31]LIU DY, LEI LM, LIAO ZH, et al.Traditional Chinese medicine in treatment of acute pancreatitis[J].J Changchun Univ Chin Med, 2015, 31 (4) :877-880. (in Chinese) 刘冬一, 雷力民, 廖昭海, 等.中医药治疗急性胰腺炎研究进展[J].长春中医药大学学报, 2015, 31 (4) :877-880.
    [32]REN XM, LI J, CHEN HJ, et al.Clinical study on Xuebijing Injection in treatment of acute pancreatitis in children[J].Drugs Clin, 2016, 31 (7) :999-1002. (in Chinese) 任晓明, 李洁, 陈赫军, 等.血必净注射液治疗儿童急性胰腺炎的临床研究[J].现代药物与临床, 2016, 31 (7) :999-1002.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (2515) PDF downloads(405) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return