Influencing factors for delayed gastric emptying after pancreaticoduodenectomy and its prevention and treatment

Hou DengFeng; Bu XianMin

doi:10.3969/j.issn.1001-5256.2018.03.050

Issue 3

Mar. 2018

Turn off MathJax

Article Contents

Abstract

References

Article Navigation > Journal of Clinical Hepatology > 2018 > 34(3): 663-666

PDF( 1571 KB)

Influencing factors for delayed gastric emptying after pancreaticoduodenectomy and its prevention and treatment

DOI: 10.3969/j.issn.1001-5256.2018.03.050

Department of Hepatobiliary and Splenic Surgery, Shengjing Hospital of China Medical University

Published Date: 2018-03-20

Abstract

Abstract

Delayed gastric emptying ( DGE) is a common complication after pancreatoduodenectomy. Due to its complex causes and difficulties in treatment, it has been a difficult problem in general surgery. By analyzing the improvement in the surgical procedure of pancreaticoduodenectomy in recent years and the influence of the establishment of predictive scoring model on DGE, this article puts forward new directions for the prevention and treatment of DGE. It is pointed out that effective preoperative assessment and reasonable selection of surgical procedures may help to reduce the incidence rate of DGE after surgery.
- pancreaticoduodenectomy,
- gastric emptying,
- complication,
- review

FullText(HTML)

References(34)

References

[1]SAHORA K, WARSHAW AL, LILLEMOE KD, et al.The effect of antecolic versus retrocolic reconstruction on delayed gastric emptying after classic non-pylorus-preserving pancreaticoduodenectomy[J].Am J Surg, 2015, 209 (6) :1028-1035.

[2]NEOPTOLEMOS JP, STOCKEN DD, DUNN JA, et al.Influence of resection margins on survival for patients with pancreatic cancer treated by adjuvant chemoradiation and/or chemotherapy in the ESPAC-1 randomized controlled trial[J].Ann Surg, 2001, 234 (6) :758-768.

[3]FUTAGAWA Y, KANEHIRA M, FURUKAWA K, et al.Impact of delayed gastric emptying after pancreaticoduodenectomy on survival[J].J Hepatobiliary Pancreat Sci, 2017, 24 (8) :466-474.

[4]WENTE MN, BASSI C, DERVENIS C, et al.Delayed gastric emptying (DGE) after pancreatic surgery:a suggested definition by the Internati-onal Study Group of Pancreatic Surgery (ISGPS) [J].Surgery, 2007, 142 (5) :761-768.

[5]LI JJ, DU Z.Clinical analysis of risk factors for postoperative gastroparesis syndrome after pancreaticoduodenectomy[J].Chin J Surg Integr Tradit West Med, 2016, 22 (3) :224-227. (in Chinese) 李进军, 杜智.胰十二指肠切除术后胃瘫的危险因素临床分析[J].中国中西医结合外科杂志, 2016, 22 (3) :224-227.

[6]GONZALEZ HC, VELANOVICH V.Enterral therapy:gastric neurostimu1ator for gastroparesis[J].Exp Rev Med Devices, 2010, 7 (3) :319-332.

[7]EL NAKEEB A, ASKR W, MAHDY Y, et al.Delayed gastric emptying after pancreaticoduodenectomy.Risk factors, predictors of severity and outcome.A single center experience of 588 cases[J].J Gastrointest Surg, 2015, 19 (6) :1093-1100.

[8]TAN HT, ZONG Y, ZHAO ZQ, et al.Prognostic factors of postoperative delayed gastric emptying after pancreaticoduodenectomy:apredictive model[J].Chin J Surg, 2017, 55 (5) :368-372. (in Chinese) 谭宏涛, 宗岩, 赵战强, 等.胰十二指肠切除术后胃排空延迟预后预测系统的建立和应用[J].中华外科杂志, 2017, 55 (5) :368-372.

[9]WALSH SR, TANG TY, FAROOQ N, et al.Perioperative fluid restriction reduce complica tions after major gastrointestinal surgery[J].Surgery, 2008, 143 (4) :466-468.

[10]ZHANG XF, LU Q, LIU C, et al.Risk factors for delayed gastric emptying after pancreaticoduodenectomy and treatment[J/CD].Chin J Hepatic Surg:Electronic Edition, 2015, 4 (6) :335-339. (in Chinese) 张谞丰, 卢强, 刘畅, 等.胰十二指肠切除术后胃排空延迟发生危险因素分析及治疗[J/CD].中华肝脏外科手术学电子杂志, 2015, 4 (6) :335-339.

[11]ALJARALLAH BM.Management of diabetic gastroparesis[J].Saudi J Gastroenterol, 2011, 17 (1) :97-104.

[12]CHENG ZM, CHENG NS, XIONG XZ, et al.Risk factors of gastric paralysis following pancreaticoduodenectomy[J].Chin J Bases Clin General Surg, 2016, 23 (8) :1018-1023. (in Chinese) 程智猛, 程南生, 熊先泽, 等.胰十二指肠切除术后胃瘫的危险因素分析[J].中国普外基础与临床杂志, 2016, 23 (8) :1018-1023.

[13]TRAVERSO LW, LONGMIRE WP JR.Preservation of the pylorus in pancreaticoduodenectomy[J].Surg Gynecol Obstet, 1978, 146 (6) :959-962.

[14] KAWAI M, TANI M, HIRONO S, et al.Pylorus ring resection reduces delayed gastric emptying in patients undergoing pancreatoduodenectomy:a prospective, randomized, controlled trial of pylorus-resecting versus pylorus-preserving pancreatoduodenectomy[J].Ann Surg, 2011, 253 (3) :495-501.

[15]KAWAI M, TANI M, HIRONO S, et al.Pylorus ring resection reduces delayed gastric emptying in patients undergoing pancreatoduodenectomy:a prospective, randomized, controlled trial of pylorus-resecting versus pylorus-preserving pancreatoduodenectomy[J].Ann Surg, 2011, 253 (3) :495-501.

[16]KAWAI M, TANI M, HIRONO S, et al.Pylorus-resecting pancreaticoduodenectomy offers long-term outcomes similar to those of pylorus-preserving pancreaticoduodenectomy:results of a prospective study[J].World J Surg, 2014, 38 (6) :1476-1483.

[17]ZHANG MJ, WANG HT, TAN XD, et al.Comparison of clinical effect between SSPPD and PPPD:a meta-analysis[J].Chin J Bases and Clin Gen Surg, 2017, 24 (3) :286-296. (in Chinese) 张明杰, 王怀涛, 谭晓冬, 等.SSPPD和PPPD的疗效比较[J].中国普外基础与临床杂志, 2017, 24 (3) :286-296.

[18]MATSUMOTO I, SHINZEKI M, ASARI S, et al.A prospective randomized comparison between pylorus-and subtotal stomachpreserving pancreatoduodenectomy on postoperative delayed gastric emptying occurrence and long-term nutritional status[J].J Surg Oncol, 2014, 109 (7) :690-696.

[19]HACKERT T, PROBST P, KNEBEL P, et al.Pylorus resection does not reduce delayed gastric emptying after partial pancreatoduodenectomy:a blinded randomized controlled trial (PROPP Study, DRKS00004191) [J].Ann Surg, 2017.[Epub ahead of print]

[20]HANNA MM, TAMARIZ L, GADDE R.Delayed gastric emptying after pylorus preserving pancreaticoduodenectomy-does gastrointestinal reconstruction technique matter[J].Am J Surg, 2016, 211 (4) :810-819.

[21]IMAMURA N, CHIJIIWA K, OHUCHIDA J, et al.Prospective randomized clinical trial of a change in gastric emptying and nutritional status after a pylorus-preserving pancreaticoduodenectomy:comparison between an antecolic and a vertical retrocolic duodenojejunostomy[J].HPB (Oxford) , 2014, 16 (4) :384-394.

[22]BARAKAT O, CAGIGAS MN, BOZORGUI S, et al.Proximal Roux-en-y gastrojejunal anastomosis with pyloric ring resection improves gastric emptying after pancreaticoduodenectomy[J].J Gastrointest Surg, 2016, 20 (5) :914-923.

[23]SHIMODA M, KUBOTA K, KATOH M, et al.Effect of billroth II or Roux-en-Y reconstruction for the gastrojejunostomy on delayed gastric emptying after pancreaticoduodenectomy:a randomized controlled study[J].Ann Surg, 2013, 257 (5) :938-942.

[24]AKIO T, TORU N, TOSHIMICHI A, et al.Delayed gastric emptying in side-to-side gastrojejunostomy in pancreaticoduodenectomy:result of a propensity score matching[J].J Gastrointest Surg, 2017, 21 (10) :1635-1642.

[25]ZHANG MJ, LIU X, TAN XD, et al.Meta-analysis of Braun enteroenterostomy in pancreatoduodenectomy[J].J Hepatopancreatobiliary Surg, 2017, 29 (1) :40-45, 56. (in Chinese) 张明杰, 刘信, 谭晓冬, 等.Braun吻合对胰十二指肠切除术后并发症影响的Meta分析[J].肝胆胰外科杂志, 2017, 29 (1) :40-45, 56.

[26]HUANG MQ, LI M, MAO JY, et al.Braun enteroenterostomy reduces delayed gastric emptying:a systematic review and meta-analysis[J].Int J Surg, 2015, 23 (Pt A) :75-81.

[27]LIAN FZ.Risk factors analysis of delayed gastric emptying after pancreatico-duodenectomy[J].J Hepatopancreatobiliary Surg, 2016, 28 (2) :109-112. (in Chinese) 连福珍.胰十二指肠切除术后胃排空延迟的危险因素分析[J].肝胆胰外科杂志, 2016, 28 (2) :109-112.

[28]BRAGA M, CAPRETTI G, PECORELLI N, et al.A prognostic score to predict major complications after pancreaticoduodenectomy[J].Ann Surg, 2011, 254 (5) :702-707, 707-708.

[29]ROBERTS KJ, SUTCLIFFE RP, MARUDANAYAGAM R, et al.Scoring system to predict pancreatic fistula after pancreaticoduodenectomy:a UK multicenter study[J].Ann Surg, 2015, 261 (6) :1191-1197.

[30]RASLAN M, GONZALEZ MC, DIAS MC, et al.Comparison of nutritional risk screening tools for predicting clinical outcomes in hospitalized patients[J].Nutrition, 2010, 26 (1-2) :721-726.

[31]SHEN Y, JUN W.Early enteral nutrition after pancreatoduodenec-tomy:a meta-analysis of randomized controlled trials[J].Langen-becks Arch Surg, 2013, 398:817-823.

[32]WANG JX, WANG JH, SAHNG YM.Effect of erythromycin in treatment of gastroparesis after gastric surgery[J].China Prac Med, 2006, 1 (1) :61-62. (in Chinese) 王景新, 王君华, 尚亚民.红霉素在治疗胃手术后胃瘫中的应用[J].中国实用医药, 2006, 1 (1) :61-62.

[33]GU FZ, ZHOU ZJ, WANG W, et al.The latest progress in the treatment of postoperative gastroparesis[J].J World Latest Med Inf, 2017, 58:43-45. (in Chinese) 谷凤志, 周志坚, 王维, 等.术后胃瘫的中西医治疗的最新进展[J].世界最新医学信息文摘, 2017, 58:43-45.

[34]LAL N, LIVEMORE S, DUNNE D, et al.Gastric electrical stimulation with the enterra system:a systematic review[J].Gastroenterol Res Pract, 2015, 2015:762972

Relative Articles

[1]	Yunchong WU, Yanyan YANG, Chuan LI, Xiaohuan WU, Shide LIN. Role of inflammatory cytokines in disorder of glucose metabolism in patients with liver cirrhosis[J]. Journal of Clinical Hepatology, 2024, 40(9): 1886-1890. doi: 10.12449/JCH240926
[2]	Zhan ZENG, Yuanjiao GAO, Xiaoyue BI, Fengxin CHEN, Wen DENG, Tingting JIANG, Yanjie LIN, Liu YANG, Minghui LI, Yao XIE. Value of HBsAg level in predicting liver inflammation in patients with HBeAg-positive chronic hepatitis B virus infection and normal alanine aminotransferase[J]. Journal of Clinical Hepatology, 2022, 38(5): 1030-1034. doi: 10.3969/j.issn.1001-5256.2022.05.011
[3]	Huaqian XU, Xue LI, Shanhong TANG. Research advances in the role of inflammatory response and related treatment strategies in acute-on-chronic liver failure[J]. Journal of Clinical Hepatology, 2022, 38(8): 1927-1930. doi: 10.3969/j.issn.1001-5256.2022.08.041
[4]	Ting LI, Huabao LIU, Wenyan HU, Chunyan RAO. Role of inflammation in hepatic fibrosis[J]. Journal of Clinical Hepatology, 2022, 38(10): 2368-2372. doi: 10.3969/j.issn.1001-5256.2022.10.032
[5]	Xinlan ZHOU, Xin MA, Yanbing WANG, Xiufen LI, Dan HUANG, Wei LU, Zhanqing ZHANG, Rongrong DING. Value of aspartate aminotransferase-to-platelet ratio index, fibrosis-4, and gamma-glutamyl transpeptidase-to-platelet ratio in diagnosis of liver inflammation grade in patients with chronic hepatitis B[J]. Journal of Clinical Hepatology, 2021, 37(9): 2066-2070. doi: 10.3969/j.issn.1001-5256.2021.09.013
[6]	Yao LI, Jingchao WANG, Jiaqi YUAN, Hao WEN, Ying ZHOU, Haining FAN, Zhixin WANG. Influence of endoplasmic reticulum stress on the secretion of some inflammatory mediators in hepatic alveolar echinococcosis[J]. Journal of Clinical Hepatology, 2021, 37(1): 131-134. doi: 10.3969/j.issn.1001-5256.2021.01.026
[7]	Wang TingShuai, Wang Na, Zhang RongZhen, Wang MingGang, Huang ShaoDong, Ma YuZhen, Wu Cong, Mao DeWen. Role of immune response and inflammatory injury in the pathogenesis of liver failure[J]. Journal of Clinical Hepatology, 2020, 36(6): 1415-1419. doi: 10.3969/j.issn.1001-5256.2020.06.050
[8]	Yin JinPing, Yue ZiChen, Zhuo ShaoYuan. STAT3: A key molecule in the progression of liver cancer mediated by chronic inflammation[J]. Journal of Clinical Hepatology, 2020, 36(4): 948-952. doi: 10.3969/j.issn.1001-5256.2020.04.054
[9]	Guo Yan, Huang Li, Yang GuoChao, Liu Shan, Du LinNa, Wang MinJuan. Association between nonalcoholic fatty liver disease and dietary inflammation index and its practical significance[J]. Journal of Clinical Hepatology, 2019, 35(10): 2324-2326. doi: 10.3969/j.issn.1001-5256.2019.10.042
[10]	Liu Li, Li JunYi, Du YingRong, Huang HongLi, Luo Yu, Li HuiMin, Li WeiKun, Wang Lin, Liu ChunYun. Influencing factors for liver inflammation grade and fibrosis degree in patients with low-level HBV DNA[J]. Journal of Clinical Hepatology, 2019, 35(5): 982-986. doi: 10.3969/j.issn.1001-5256.2019.05.010
[11]	He Yang, Su YaRong, Han ZiYan. Current status of research on primary and secondary risk factors for esophagogastric variceal rebleeding in patients with liver cirrhosis[J]. Journal of Clinical Hepatology, 2018, 34(7): 1555-1559. doi: 10.3969/j.issn.1001-5256.2018.07.041
[12]	Wang WanQin, Wen MaoYao, Fan XiaoLi, Shen Yi, Yang XiaoXue, Yang Li. Research advances in liver cirrhosis complicated by portal vein thrombosis[J]. Journal of Clinical Hepatology, 2016, 32(7): 1409-1412. doi: 10.3969/j.issn.1001-5256.2016.07.045
[13]	Zhang XinTong, Qi XingShun, Gao Fan, Guo XiaoZhong. Research advances in venous thromboembolism in patients with liver cirrhosis[J]. Journal of Clinical Hepatology, 2016, 32(10): 2004-2006. doi: 10.3969/j.issn.1001-5256.2016.10.043
[14]	Li Qiang, Huang YuXian, Chen Liang. Simple serum markers for significant liver inflammation in chronic hepatitis B patients with an alanine aminotransferase level lower than 2 times upper limit of normal[J]. Journal of Clinical Hepatology, 2016, 32(6): 1125-1129. doi: 10.3969/j.issn.1001-5256.2016.06.021
[15]	Ding Jie, Wang Liang, Li Juan, Kong Yin, Zhao Rui, He JingJing, Li GuangMing, Wang JuanXia, Zhang LingYi. Changes in serum asymmetric dimethylarginine levels in progression of liver inflammation in an experimental rat model of nonalcoholic fatty liver disease[J]. Journal of Clinical Hepatology, 2016, 32(1): 148-151. doi: 10.3969/j.issn.1001-5256.2016.01.029
[16]	Zhu JuanJuan, Cheng MingLiang, Zhao XueKe. Role of liver immunological inflammation in development and progression of nonalcoholic fatty liver disease[J]. Journal of Clinical Hepatology, 2016, 32(3): 570-573. doi: 10.3969/j.issn.1001-5256.2016.03.038
[17]	Wu YuJing, Guo JinSheng. Hepatic stellate cells,Toll-like receptor 4 signaling pathway,and inflammatory fibrotic microenvironment in the development of hepatocellular carcinoma[J]. Journal of Clinical Hepatology, 2015, 31(6): 876-879. doi: 10.3969/j.issn.1001-5256.2015.06.012
[18]	Wang JingYun, Sun Jing, Gao YanHang. Research advances in liver cirrhosis complicated by bacteremia[J]. Journal of Clinical Hepatology, 2014, 30(7): 683-686. doi: 10.3969/j.issn.1001-5256.2014.07.030
[19]	Dong HongYun, Zhao GuiMing, Li Ying. Study on the relationship between inflammation activity in the liver tissues and expression of HBcAg in patients with chronic hepatits B[J]. Journal of Clinical Hepatology, 2007, 23(1): 13-14.

Supplements(0)

Cited By

Cited by

Periodical cited type(2)

1.	魏文敏. 血脂指标与血清转氨酶、胆碱酯酶、γ-谷氨酰转肽酶联合检验在非酒精性脂肪肝病诊断中的应用. 中外医学研究. 2024(20): 78-81 .
2.	胡丽军，连倩倩. 超声声衰减成像定量参数联合RC/HDL-C诊断MAFLD肝脂肪变程度的效能及与脂代谢的相关性. 肝脏. 2024(10): 1260-1264 .

Other cited types(0)

Proportional views

Proportional views

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Get Citation

PDF

XML

Article Metrics

Article views (2620) PDF downloads(434)

Influencing factors for delayed gastric emptying after pancreaticoduodenectomy and its prevention and treatment

DOI: 10.3969/j.issn.1001-5256.2018.03.050