Current status of anxiety and depression among hepatitis B patients in Shanghai, China and related influencing factors

Objective To investigate the prevalence of anxiety and depression among hepatitis B patients in Shanghai, China and related influencing factors. Methods A cross-sectional survey was performed among 917 hepatitis B patients who were treated in Shanghai East Hospital, Tongji University, Shanghai Public Health Clinical Center, and Nanhua Hospital in Pudong New Area from June to December, 2016. The Hospital Anxiety and Depression Scale ( HADS) and a self-designed social demography questionnaire were used for evaluation.The independent samples t-test and a one-way analysis of variance were used for comparison of continuous data between groups, and a multivariate linear regression analysis was used to analyze the correlation of anxiety and depression scores with demographic and socioeconomic factors. Results The prevalence rates of anxiety and depression symptoms assessed by HADS were 87. 6% and 90. 7%, respectively.The severity of anxiety in hepatitis B patients was associated with age, family income, and educational level ( F = 3. 518, 6. 416, and3. 322, all P < 0. 05) , and the severity of depression was associated with age, marital status, family income, occupation, and complications ( F = 2. 904, t = 2. 242, F = 22. 840, F = 9. 235, F = 11. 870, t = 2. 246, all P < 0. 05) . High educational level, high income, and single status were risk factors for depression ( all P < 0. 05) , and high income and the increase in age were significantly associated with anxiety ( all P < 0. 05) . Conclusion At present, the mental state of hepatitis B patients in Shanghai is not optimistic, with high prevalence rates of anxiety and depression. The results remind medical workers that they should pay attention to the mental health of hepatitis B patients.