Value of endoscopic ultrasonography in diagnosis of pancreatic space-occupying diseases

Wu Bin; Shen YiYu; Chen XuJian; Zhong Hai; Wang XiaoGuang; Song ZhengWei; Zhong ZhengXiang

doi:10.3969/j.issn.1001-5256.2018.08.026

Issue 8

Aug. 2018

Turn off MathJax

Article Contents

Abstract

References

Article Navigation > Journal of Clinical Hepatology > 2018 > 34(8): 1723-1727

PDF( 2074 KB)

Value of endoscopic ultrasonography in diagnosis of pancreatic space-occupying diseases

DOI: 10.3969/j.issn.1001-5256.2018.08.026

Department of Hepatopancreatobiliary Surgery, The Second Affiliated Hospital of Jiaxing College

Received Date: 2018-01-11
Published Date: 2018-08-20

Abstract

Abstract

Objective To investigate the value of endoscopic ultrasonography ( EUS) in the diagnosis of pancreatic space-occupying diseases. Methods A total of 85 patients with suspected pancreatic space-occupying diseases who were treated in The Second Affiliated Hospital of Jiaxing College from January 2015 to January 2017 were enrolled. Surgical pathological results or follow-up results were used as the gold standard for evaluating the value of EUS and EUS-guided fine needle aspiration ( EUS-FNA) in the diagnosis of pancreatic space-occupying diseases. The chi-square test was used for comparison of categorical data between groups. Results EUS had an imaging detection rate of 96. 7% ( 59/61) , a specificity of 100% ( 24/24) , and an accuracy rate of 97. 6% ( 83/85) in the diagnosis of pancreatic space-occupying diseases; EUS had significantly higher detection rate and accuracy rate than abdominal ultrasound, computed tomography, and magnetic resonance imaging ( detection rate: χ2= 4. 344, 3. 873, and 15. 445, all P < 0. 05; accuracy rate: χ2= 6. 675, 8. 685, and 17. 389, all P <0. 05) . EUS-FNA had a detection rate of 81. 8% ( 45/55) and an accuracy rate of 81. 0% ( 47/58) . Among the patients who underwent surgery to have pathological results, the overall coincidence rate of preoperative EUS-FNA was 84. 2% ( 16/19) . Conclusion Compared with conventional imaging examinations, EUS has a higher diagnostic accuracy for pancreatic space-occupying diseases, and EUS-FNA can further clarify the nature and pathological type of space-occupying lesions. EUS may help with the early diagnosis and treatment of pancreatic tumors.
- endoscopic ultrasonography,
- pancreatic neoplasms,
- biopsy, needle,
- dignosis

FullText(HTML)

References(13)

References

[1]QU GB, SONG MM.Early diagnosis and treatment of pancreatic cancer[J].Int J Surg, 2017, 44 (6) :364-367. (in Chinese) 曲更宝, 宋茂民.胰腺癌的早期诊断和治疗进展[J].国际外科学杂志, 2017, 44 (6) :364-367.

[2]ZHANG ST, WANG YJ.How to make better use of gastrointestinal endoscopy in diagnosis and treatment of biliary and pancreatic diseases[J].J Clin Hepatol, 2017, 33 (4) :607-610. (in Chinese) 张澍田, 王拥军.如何更好地利用消化内镜诊治胆胰疾病[J].临床肝胆病杂志, 2017, 33 (4) :607-610.

[3]LIU YM.The role of endoscopic ultrasound in detection of small pancreatic tumors[J].China Oncol, 2017, 27 (3) :233-236. (in Chinese) 刘玉美.超声内镜对胰腺小肿瘤的诊断价值[J].中国癌症杂志, 2017, 27 (3) :233-236.

[4]HOU XJ, JIN ZD.Diagnostic value of endoscopic ultrasonography for pancreatic head mass[J].J Clin Hepatol, 2014, 30 (12) :1255-1258. (in Chinese) 侯晓佳, 金震东.超声内镜检查在胰头占位性病灶中的诊断价值[J].临床肝胆病杂志, 2014, 30 (12) :1255-1258.

[5]MAGUCHI H.The roles of endoscopic ultrasonography in the diagnosis of pancreatic tumors[J].J Hepatobiliary Pancreat Surg, 2004, 11 (1) :1-3.

[6]KITANO M, KUDO M, YAMAO K, et al.Characterization of small solid tumors in the pancreas:The value of contrast-enhanced harmonic endoscopic ultrasonography[J].Am J Gastroenterol, 2012, 107 (2) :303-310.

[7]HANADA K, OKAZAKI A, HIRANO N, et al.Effective screening for early diagnosis of pancreatic cancer[J].Best Pract Res Clin Gastroenterol, 2015, 29 (6) :929-939.

[8]SUN R, GAO XL, MA YX.Application of bile duct and pancreatic duct dilatation in the diagnosis of pancreatic cancer by ultrasound[J].Chin J Mod Drug Appl, 2016, 10 (13) :60-61. (in Chinese) 孙瑞, 高晓丽, 马悦霞.胆管、胰管扩张在超声诊断胰腺癌中的应用价值分析[J].中国现代药物应用, 2016, 10 (13) :60-61.

[9]HE Q, XU YQ.Application of endoscopic ultrasonography in diagnosis of pancreatic cancer and related research advances[J].J Clin Hepatol, 2016, 32 (7) :1280-1282. (in Chinese) 何强, 徐有青.超声内镜在胰腺癌诊断中的应用及进展[J].临床肝胆病杂志, 2016, 32 (7) :1280-1282.

[10]JIANG HM.Clinical significance of endoscopic ultrasonography in TNM staging of gastric cancer[J].Med J Ind Enterpr, 2014, 27 (1) :586-587. (in Chinese) 蒋汉梅.超声内镜对胃癌TNM分期的临床意义[J].工企医刊, 2014, 27 (1) :586-587.

[11]SUN L.Diagnostic value of color Doppler ultrasound for mass type pancreatitis and pancreatic cancer[J].Hebei Med J, 2016, 38 (12) :1816-1818. (in Chinese) 孙雷.彩色多普勒超声对肿块型胰腺炎和胰腺癌的诊断价值[J].河北医药, 2016, 38 (12) :1816-1818.

[12]QIN SY, JIANG HX, LI P, et al.The diagnostic value of endoscopic ultrasound-guided fine-needle aspiration biopsy of cell block with immunostaining for pancreatic lesions[J].Chin J Dig Endosc, 2014, 31 (6) :312-316. (in Chinese) 覃山羽, 姜海行, 李萍, 等.细胞块结合免疫组化在内镜超声引导下穿刺诊断胰腺实性占位中的应用价值[J].中华消化内镜杂志, 2014, 31 (6) :312-316.

[13]HUANG Q, LIU CH, PENG B, et al.The diagnostic value and safety of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) in pancreatic lesions[J].J Hepatobiliary Surg, 2016, 24 (3) :175-178. (in Chinese) 黄强, 刘臣海, 彭斌, 等.超声内镜引导下细针穿刺活检 (EUS-FNA) 在胰腺占位性病变中的诊断价值及安全性评估[J].肝胆外科杂志, 2016, 24 (3) :175-178.

Relative Articles

[1]	Yafen TANG, Zhiyang JIANG, Dan LONG, Jinmin CHEN, Shan GAO. Efficacy of endoscopic ultrasound-guided coil placement combined with tissue adhesive injection in treatment of gastric varices with spontaneous shunt[J]. Journal of Clinical Hepatology, 2024, 40(4): 739-744. doi: 10.12449/JCH240416
[2]	Hongzhao SONG, Tongtong LI, Zhenan LI, Junmin WANG. Advances in the application of endoscopic ultrasonography in the diagnosis and treatment of cholangiocarcinoma[J]. Journal of Clinical Hepatology, 2024, 40(11): 2338-2344. doi: 10.12449/JCH241132
[3]	National Clinical Research Center for Digestive Diseases (Shanghai), Professional Committee of Pancreatic Disease, Chinese Medical Doctor Association. Chinese guidelines for the diagnosis and treatment of pancrestic cystic neoplasm(2022)[J]. Journal of Clinical Hepatology, 2023, 39(2): 290-298. doi: 10.3969/j.issn.1001-5256.2023.02.007
[4]	Yuanzhen HAO, Rui CHENG, Shutian ZHANG. Application of endoscopic ultrasound in the diagnosis and treatment of pancreatic diseases[J]. Journal of Clinical Hepatology, 2022, 38(12): 2681-2686. doi: 10.3969/j.issn.1001-5256.2022.12.001
[5]	Jing LI, Xin LI, Hui ZHANG, Youqing XU. Value of contrast-enhanced endoscopic ultrasound versus contrast-enhanced computed tomography in the diagnosis of pancreatic solid space-occupying lesions[J]. Journal of Clinical Hepatology, 2021, 37(7): 1648-1651. doi: 10.3969/j.issn.1001-5256.2021.07.033
[6]	Hailun MENG, Suwen LI, Yulin SONG, Junjun BAO, Heng LIU, Qiao MEI. Effect of different cytopathological grading standards on the diagnosis of pancreatic cancer by endoscopic ultrasound-guided fine needle aspiration[J]. Journal of Clinical Hepatology, 2021, 37(2): 390-395. doi: 10.3969/j.issn.1001-5256.2021.02.028
[7]	Yang Fan, Yang Fei, Sun SiYu. Endoscopic ultrasound diagnosis of space-occupying lesions in the pancreas[J]. Journal of Clinical Hepatology, 2020, 36(8): 1704-1709. doi: 10.3969/j.issn.1001-5256.2020.08.005
[8]	Wang Lei, Zou DuoWu, Li ZhaoShen. Application of endoscopic ultrasound in the diagnosis of autoimmune pancreatitis[J]. Journal of Clinical Hepatology, 2018, 34(8): 1609-1613. doi: 10.3969/j.issn.1001-5256.2018.08.004
[9]	Zhang MingMing, Li YanQing. Application of needle- based confocal laser endomicroscopy in diagnosis of pancreatic cystic lesions[J]. Journal of Clinical Hepatology, 2017, 33(1): 49-52. doi: 10.3969/j.issn.1001-5256.2017.01.010
[10]	Zheng SuLi, Zhang TaiPing. An excerpt of laparoscopic surgery for pancreatic neoplasms: the European Association for Endoscopic Surgery clinical consensus conference（2017）[J]. Journal of Clinical Hepatology, 2017, 33(5): 816-819. doi: 10.3969/j.issn.1001-5256.2017.05.004
[11]	Wen HongXu, Xue DiQiang, Du HongWei, Ming YuZhen. Common bile duct wall puncture and biopsy guided by endoscopic ultrasonography in diagnosis of common bile duct malignant tumor:a case report[J]. Journal of Clinical Hepatology, 2017, 33(7): 1346-1348. doi: 10.3969/j.issn.1001-5256.2017.07.031
[12]	Lu: Yan, Zhang XiaoWen. Classification and diagnosis of pancreatic cystic neoplasm[J]. Journal of Clinical Hepatology, 2016, 32(5): 968-971. doi: 10.3969/j.issn.1001-5256.2016.05.039
[13]	He Qiang, Xu YouQing. Application of endoscopic ultrasonography in diagnosis of pancreatic cancer and related research advances[J]. Journal of Clinical Hepatology, 2016, 32(7): 1280-1282. doi: 10.3969/j.issn.1001-5256.2016.07.012
[14]	Hou XiaoJia, Jin ZhenDong. Progress in additional new techniques of endoscopic ultrasound in treatment of pancreatic tumors[J]. Journal of Clinical Hepatology, 2015, 31(5): 671-673. doi: 10.3969/j.issn.1001-5256.2015.05.008
[15]	Hou XiaoJia, Jin ZhenDong. Diagnostic value of endoscopic ultrasonography for pancreatic head mass[J]. Journal of Clinical Hepatology, 2014, 30(12): 1255-1258. doi: 10.3969/j.issn.1001-5256.2014.12.007
[16]	Zhang WenYing, Jin ZhenDong. Diagnostic and therapeutic value of endoscopic ultrasonography for pancreatic cancer[J]. Journal of Clinical Hepatology, 2013, 29(1): 50-53.
[17]	Chen Jie. Pathological and differential diagnoses of exocrine pancreatic tumors[J]. Journal of Clinical Hepatology, 2013, 29(1): 45-49.
[18]	Yang Lei, Zhang Bin, Li ZhangFeng, Qiu YunFeng, Liu Yang. Diagnosis and management of intraductal papillary mucinous neoplasm in pancreas (IPMN) by endoscopy[J]. Journal of Clinical Hepatology, 2012, 28(2): 108-110+117.
[19]	Zhang WenYing, Jin ZhenDong. Endoscopic ultrasound -guided treatment for pancreatic tumor[J]. Journal of Clinical Hepatology, 2012, 28(8): 573-575+578.
[20]	Guo XiaoZhong. Advances in the diagnosis of small pancreatic cancer [J]. Journal of Clinical Hepatology, 2010, 26(5): 459-461+467.

Supplements(0)

Cited By

Cited by

Periodical cited type(7)

1.	李鑫鑫，李安庆，钟晓琴，王峰，窦迎春，赵卫东. 超声内镜、增强CT对胆胰肿瘤诊断价值的对比研究. 现代消化及介入诊疗. 2023(01): 104-108 .
2.	郭明浩，王清踪，史鑫，杜杰. ERCP联合eyemax对胆管癌的诊断价值. 中国普通外科杂志. 2023(08): 1277-1281 .
3.	严欢，贾皑，张娟，李红霞. 超声内镜引导细针穿刺活检对胰腺占位性疾病的诊断价值. 西安交通大学学报(医学版). 2020(03): 425-428 .
4.	周艳，宁波. 胰液中循环游离DNA甲基化异常在胰腺癌早期诊断中的应用. 临床肝胆病杂志. 2020(09): 2145-2148 . 本站查看
5.	张建伟，姬静伟，邢明轩，王广义，杜晓宏. 胰腺原发脂肪肉瘤1例报告. 临床肝胆病杂志. 2019(04): 866-867 . 本站查看
6.	吴燕彬，朱花敏，王学文，牛洪凯，成雨. 实时弹性成像对胰十二指肠切除术后胰瘘的预测价值. 临床肝胆病杂志. 2019(07): 1541-1545 . 本站查看
7.	焦德超，雷钦宇，韩新巍，李宗明，毕永华，张全会. 超细电子软式内镜联合腔道超声辅助经皮肝穿刺胆管内钳夹活组织检查的临床应用. 临床肝胆病杂志. 2019(12): 2744-2747 . 本站查看

Other cited types(5)

Proportional views

Proportional views

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Get Citation

PDF

XML

Article Metrics

Article views (2312) PDF downloads(376)

Value of endoscopic ultrasonography in diagnosis of pancreatic space-occupying diseases

DOI: 10.3969/j.issn.1001-5256.2018.08.026