Value of endoscopic ultrasonography in diagnosis of pancreatic space-occupying diseases

Wu Bin; Shen YiYu; Chen XuJian; Zhong Hai; Wang XiaoGuang; Song ZhengWei; Zhong ZhengXiang

doi:10.3969/j.issn.1001-5256.2018.08.026

Issue 8

Aug. 2018

Turn off MathJax

Article Contents

Abstract

References

Article Navigation > Journal of Clinical Hepatology > 2018 > 34(8): 1723-1727

PDF( 2074 KB)

Value of endoscopic ultrasonography in diagnosis of pancreatic space-occupying diseases

DOI: 10.3969/j.issn.1001-5256.2018.08.026

Department of Hepatopancreatobiliary Surgery, The Second Affiliated Hospital of Jiaxing College

Received Date: 2018-01-11
Published Date: 2018-08-20

Abstract

Abstract

Objective To investigate the value of endoscopic ultrasonography ( EUS) in the diagnosis of pancreatic space-occupying diseases. Methods A total of 85 patients with suspected pancreatic space-occupying diseases who were treated in The Second Affiliated Hospital of Jiaxing College from January 2015 to January 2017 were enrolled. Surgical pathological results or follow-up results were used as the gold standard for evaluating the value of EUS and EUS-guided fine needle aspiration ( EUS-FNA) in the diagnosis of pancreatic space-occupying diseases. The chi-square test was used for comparison of categorical data between groups. Results EUS had an imaging detection rate of 96. 7% ( 59/61) , a specificity of 100% ( 24/24) , and an accuracy rate of 97. 6% ( 83/85) in the diagnosis of pancreatic space-occupying diseases; EUS had significantly higher detection rate and accuracy rate than abdominal ultrasound, computed tomography, and magnetic resonance imaging ( detection rate: χ2= 4. 344, 3. 873, and 15. 445, all P < 0. 05; accuracy rate: χ2= 6. 675, 8. 685, and 17. 389, all P <0. 05) . EUS-FNA had a detection rate of 81. 8% ( 45/55) and an accuracy rate of 81. 0% ( 47/58) . Among the patients who underwent surgery to have pathological results, the overall coincidence rate of preoperative EUS-FNA was 84. 2% ( 16/19) . Conclusion Compared with conventional imaging examinations, EUS has a higher diagnostic accuracy for pancreatic space-occupying diseases, and EUS-FNA can further clarify the nature and pathological type of space-occupying lesions. EUS may help with the early diagnosis and treatment of pancreatic tumors.
- endoscopic ultrasonography,
- pancreatic neoplasms,
- biopsy, needle,
- dignosis

FullText(HTML)

References(13)

References

[1]QU GB, SONG MM.Early diagnosis and treatment of pancreatic cancer[J].Int J Surg, 2017, 44 (6) :364-367. (in Chinese) 曲更宝, 宋茂民.胰腺癌的早期诊断和治疗进展[J].国际外科学杂志, 2017, 44 (6) :364-367.

[2]ZHANG ST, WANG YJ.How to make better use of gastrointestinal endoscopy in diagnosis and treatment of biliary and pancreatic diseases[J].J Clin Hepatol, 2017, 33 (4) :607-610. (in Chinese) 张澍田, 王拥军.如何更好地利用消化内镜诊治胆胰疾病[J].临床肝胆病杂志, 2017, 33 (4) :607-610.

[3]LIU YM.The role of endoscopic ultrasound in detection of small pancreatic tumors[J].China Oncol, 2017, 27 (3) :233-236. (in Chinese) 刘玉美.超声内镜对胰腺小肿瘤的诊断价值[J].中国癌症杂志, 2017, 27 (3) :233-236.

[4]HOU XJ, JIN ZD.Diagnostic value of endoscopic ultrasonography for pancreatic head mass[J].J Clin Hepatol, 2014, 30 (12) :1255-1258. (in Chinese) 侯晓佳, 金震东.超声内镜检查在胰头占位性病灶中的诊断价值[J].临床肝胆病杂志, 2014, 30 (12) :1255-1258.

[5]MAGUCHI H.The roles of endoscopic ultrasonography in the diagnosis of pancreatic tumors[J].J Hepatobiliary Pancreat Surg, 2004, 11 (1) :1-3.

[6]KITANO M, KUDO M, YAMAO K, et al.Characterization of small solid tumors in the pancreas:The value of contrast-enhanced harmonic endoscopic ultrasonography[J].Am J Gastroenterol, 2012, 107 (2) :303-310.

[7]HANADA K, OKAZAKI A, HIRANO N, et al.Effective screening for early diagnosis of pancreatic cancer[J].Best Pract Res Clin Gastroenterol, 2015, 29 (6) :929-939.

[8]SUN R, GAO XL, MA YX.Application of bile duct and pancreatic duct dilatation in the diagnosis of pancreatic cancer by ultrasound[J].Chin J Mod Drug Appl, 2016, 10 (13) :60-61. (in Chinese) 孙瑞, 高晓丽, 马悦霞.胆管、胰管扩张在超声诊断胰腺癌中的应用价值分析[J].中国现代药物应用, 2016, 10 (13) :60-61.

[9]HE Q, XU YQ.Application of endoscopic ultrasonography in diagnosis of pancreatic cancer and related research advances[J].J Clin Hepatol, 2016, 32 (7) :1280-1282. (in Chinese) 何强, 徐有青.超声内镜在胰腺癌诊断中的应用及进展[J].临床肝胆病杂志, 2016, 32 (7) :1280-1282.

[10]JIANG HM.Clinical significance of endoscopic ultrasonography in TNM staging of gastric cancer[J].Med J Ind Enterpr, 2014, 27 (1) :586-587. (in Chinese) 蒋汉梅.超声内镜对胃癌TNM分期的临床意义[J].工企医刊, 2014, 27 (1) :586-587.

[11]SUN L.Diagnostic value of color Doppler ultrasound for mass type pancreatitis and pancreatic cancer[J].Hebei Med J, 2016, 38 (12) :1816-1818. (in Chinese) 孙雷.彩色多普勒超声对肿块型胰腺炎和胰腺癌的诊断价值[J].河北医药, 2016, 38 (12) :1816-1818.

[12]QIN SY, JIANG HX, LI P, et al.The diagnostic value of endoscopic ultrasound-guided fine-needle aspiration biopsy of cell block with immunostaining for pancreatic lesions[J].Chin J Dig Endosc, 2014, 31 (6) :312-316. (in Chinese) 覃山羽, 姜海行, 李萍, 等.细胞块结合免疫组化在内镜超声引导下穿刺诊断胰腺实性占位中的应用价值[J].中华消化内镜杂志, 2014, 31 (6) :312-316.

[13]HUANG Q, LIU CH, PENG B, et al.The diagnostic value and safety of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) in pancreatic lesions[J].J Hepatobiliary Surg, 2016, 24 (3) :175-178. (in Chinese) 黄强, 刘臣海, 彭斌, 等.超声内镜引导下细针穿刺活检 (EUS-FNA) 在胰腺占位性病变中的诊断价值及安全性评估[J].肝胆外科杂志, 2016, 24 (3) :175-178.

Relative Articles

[1]	Yunchong WU, Yanyan YANG, Chuan LI, Xiaohuan WU, Shide LIN. Role of inflammatory cytokines in disorder of glucose metabolism in patients with liver cirrhosis[J]. Journal of Clinical Hepatology, 2024, 40(9): 1886-1890. doi: 10.12449/JCH240926
[2]	Zixiang GAO, Zhongliang SHEN, Jing LIU, Youhua XIE. Research advances in cytokines in the treatment of chronic hepatitis B[J]. Journal of Clinical Hepatology, 2022, 38(8): 1710-1715. doi: 10.3969/j.issn.1001-5256.2022.08.002
[3]	Huang ZhiQin, Huang HuiFang. Research advances in cytokines associated with primary biliary cholangitis[J]. Journal of Clinical Hepatology, 2020, 36(2): 446-450. doi: 10.3969/j.issn.1001-5256.2020.02.047
[4]	Zhang Yu, Shao YueMing, Qin TingTing, Yin Xin, Wen XiaoYu. Current research status and application value of cytokines in drug-induced liver injury[J]. Journal of Clinical Hepatology, 2020, 36(8): 1883-1886. doi: 10.3969/j.issn.1001-5256.2020.08.045
[5]	Wei XinHuan, Liu YaLi, Zhang Jing, Lin Wei. Expression and significance of cytokines in children with acute hepatitis A[J]. Journal of Clinical Hepatology, 2019, 35(9): 1942-1945. doi: 10.3969/j.issn.1001-5256.2019.09.011
[6]	Xiang Jiao, Jia XiaoDong, Lu ShanShan, Wu DaWei, Zhang Ting, Dong JinKe, Huang JiaGan, Li YinYin, Yang Bin, Xu Yong, Dong Zheng, Lu Ying, Zeng Zhen, Lu YinYing. Effect of cryoablation versus microwave ablation on clinical indices and cytokines in patients with hepatocellular carcinoma[J]. Journal of Clinical Hepatology, 2019, 35(8): 1728-1733. doi: 10.3969/j.issn.1001-5256.2019.08.016
[7]	Xu Ying, Zhang DingQi, Chen JiaMei, Liu Wei, Liu Ping. Effect of various cells on the activation of hepatic stellate cells in liver microenvironment[J]. Journal of Clinical Hepatology, 2019, 35(2): 424-430. doi: 10.3969/j.issn.1001-5256.2019.02.042
[8]	Liu Zhao, Ma WenTing, Zhang PengFei, Li JinKui, Xiao JianXi, Lei JunQiang. Research advances in molecular imaging of hepatocellular carcinoma[J]. Journal of Clinical Hepatology, 2018, 34(4): 872-876. doi: 10.3969/j.issn.1001-5256.2018.04.038
[9]	Wu Han, Li ZhenLi, Xing Hao, Wang MingDa, Wu MengChao, Yang Tian. Research advances in the structure and function of osteopontin and its effect in diagnosis and treatment of hepatocellular carcinoma[J]. Journal of Clinical Hepatology, 2018, 34(9): 1999-2003. doi: 10.3969/j.issn.1001-5256.2018.09.036
[10]	Huang YongJie, Wu DeQuan, Yuan JunHui. Current status of treatment of primary hepatocellular carcinoma in the elderly population[J]. Journal of Clinical Hepatology, 2018, 34(6): 1313-1317. doi: 10.3969/j.issn.1001-5256.2018.06.039
[11]	Sheng QingShou, Lai GuoQuan, Yu XueJing, Wei Cui. The role of traditional Chinese medicine in regulating cytokines associated with liver fibrosis[J]. Journal of Clinical Hepatology, 2018, 34(12): 2677-2680. doi: 10.3969/j.issn.1001-5256.2018.12.037
[12]	Zhang ZeYu, Cheng HongYan. Clinical application of positron emission tomography/computed tomography in hepatocellular carcinoma and related research advances[J]. Journal of Clinical Hepatology, 2017, 33(7): 1365-1368. doi: doi:10.3969/j.issn.1001-5256.2017.07.036
[13]	Chen WeiBo, Cai HuiHua, Yang Yue, Chen XueMin, Jiang Yong, Sun DongLin. Research advances in regorafenib in treatment of hepatocellular carcinoma[J]. Journal of Clinical Hepatology, 2017, 33(12): 2425-2428. doi: 10.3969/j.issn.1001-5256.2017.12.039
[14]	Yang Liu, Zhu XiLing, Li Gong. Expression of programmed death-ligand 1 in hepatocellular carcinoma and its clinical significance[J]. Journal of Clinical Hepatology, 2016, 32(8): 1630-1634. doi: 10.3969/j.issn.1001-5256.2016.08.047
[15]	Zhang LiangJie, Chen HuiJuan, Zhao ShouSong. Effects of artificial liver plasma exchange on cytokines in patients with liver failure[J]. Journal of Clinical Hepatology, 2015, 31(4): 578-581. doi: 10.3969/j.issn.1001-5256.2015.04.024
[16]	Mao YiJia, Mao XiaoRong, Jiang Ni. Recent research on association between gene polymorphisms of IL-28B and other cytokines and HCV infection[J]. Journal of Clinical Hepatology, 2015, 31(8): 1347-1350. doi: 10.3969/j.issn.1001-5256.2015.08.044
[17]	Ma DeNing, Zhu XiaoDong, Tang ZhaoYou. Role of cancer- associated fibroblasts in growth and metastasis of hepatocellular carcinoma[J]. Journal of Clinical Hepatology, 2014, 30(9): 865-868. doi: 10.3969/j.issn.1001-5256.2014.09.007
[18]	Zhang Ye, Zhang MingJie, Jia ZhanSheng. Research advances in cellular immunotherapy for primary hepatocellular carcinoma[J]. Journal of Clinical Hepatology, 2014, 30(9): 860-864. doi: 10.3969/j.issn.1001-5256.2014.09.006
[19]	Zhou Jian, Wan Hong. Relationship between changes in serum cytokine levels after artificial liver therapy and clinical prognosis in patients with liver failure[J]. Journal of Clinical Hepatology, 2013, 29(7): 535-537. doi: 1001-5256 (2013) 07-0535-03
[20]	Guan HaiTao, Zhao JinLi, Tang Rui, Sun LinLin. IL-17 promotes expression of fibrosis-related factors in hepatic stellate cells[J]. Journal of Clinical Hepatology, 2013, 29(5): 370-374.

Supplements(0)

Cited By

Cited by

Periodical cited type(10)

1.	李晏杰，王娜，王沙，唐鲲，毛德文，石清兰，龙富立. HBV相关性肝衰竭发病中的Th细胞免疫调控机制及中医药干预的研究进展. 内蒙古中医药. 2023(11): 134-138 .
2.	霍瑞静，张翠丽，李静，何晨熙，李帅，高健. NF-κB信号通路对慢性乙型肝炎患者Th17/Treg相关细胞因子水平变化的影响. 中华医院感染学杂志. 2022(17): 2570-2573 .
3.	黄杏，刘文志，陈斌. 清温并用法治疗肝衰竭的中医理论及作用机制探讨. 中国医学创新. 2021(10): 164-167 .
4.	陈斌，丁秀丽，彭杰，黎运芳，王若宇，周意. 清温并用法对慢加急性肝衰竭肠源性内毒素血症大鼠结肠组织FoxP3, ROR-γt表达的影响. 中国实验方剂学杂志. 2020(02): 19-25 .
5.	谭年花，陈斌，彭杰，朱文芳，张涛，周意，王若宇. 乙肝相关性慢加急性肝衰竭“阳黄-阴阳黄-阴黄”不同证候分型患者Treg/Th17的表达. 中国实验方剂学杂志. 2020(02): 33-38 .
6.	陈斌，黎运芳，张涛，朱文芳，彭杰，张茜茜. 清温并用法对慢加急性肝衰竭大鼠肝组织Treg/Th17型细胞因子及转录因子的影响. 中华中医药杂志. 2020(09): 4618-4622 .
7.	李薇，于佳卉，王新婷，王春梅，李贺，陈建光，孙靖辉. 北五味子总木脂素对环磷酰胺诱导的免疫功能低下小鼠的调节作用. 吉林大学学报(医学版). 2019(02): 294-299+472 .
8.	陈斌，彭杰，张涛，朱文芳，张茜茜，丁秀丽，黎运芳. 清温并用法对慢加急性肝衰竭大鼠结肠组织调节性T淋巴细胞/辅助性T淋巴细胞17细胞因子的影响. 湖南中医药大学学报. 2019(05): 573-577 .
9.	张龙跃，张序瑞. 赤芍解毒汤保留灌肠治疗慢加急性肝衰竭临床研究. 系统医学. 2019(13): 138-140 .
10.	梁琼，赵隽，苏静，梁琳，张吉发. 凉血化瘀解毒法对急性肝衰竭模型大鼠免疫功能、Toll样受体及VEGF表达的影响. 中国中医急症. 2019(10): 1700-1704 .

Other cited types(5)

Proportional views

Proportional views

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Get Citation

PDF

XML

Article Metrics

Article views (2311) PDF downloads(376)

Value of endoscopic ultrasonography in diagnosis of pancreatic space-occupying diseases

DOI: 10.3969/j.issn.1001-5256.2018.08.026