|
[1] ISHIKAWA H, BARBER GN. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling[J]. Cytokine, 2009, 48 (1-2) :674-678.
|
|
[2] SOKOLOWSKA O, NOWIS D. STING signaling in cancer cells:Important or not?[J]. Arch Immunol Ther Exp (Warsz) , 2017, 66 (2) :125-132.
|
|
[3] BANETE A, SEAVER K, BAKSHI D, et al. On taking the STING out of immune activation[J]. J Leukoc Biol, 2018, 103:1189-1195.
|
|
[4] ZHONG B, YANG Y, LI S, et al. The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation[J]. Immunity, 2008, 29 (4) :538-550.
|
|
[5] SUN W, LI Y, CHEN L, et al. ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization[J]. Proc Natl Acad Sci U S A, 2009, 106 (21) :8653-8658.
|
|
[6] QIAO JT, CUI C, QING L, et al. Activation of the STINGIRF3 pathway promotes hepatocyte inflammation, apoptosis and induces metabolic disorders in nonalcoholic fatty liver disease[J]. Metabolism, 2018, 81:13-24.
|
|
[7] JIN L, XU LG, YANG IV, et al. Identification and characterization of a loss-of-function human MPYS variant[J]. Genes Immun, 2011, 12 (4) :263-269.
|
|
[8] XU YY, WANG YY, XU HG, et al. Identification and characterization of stimulator of interferon gene promoter[J]. Acta Univ Med Nanjing:Natural Sci, 2016, 36 (7) :783-787. (in Chinese) 徐妍妍, 王艳艳, 徐华国, 等.小鼠STING基因启动子的克隆鉴定及功能初步分析[J].南京医科大学学报:自然科学版, 2016, 36 (7) :783-787.
|
|
[9] KRANZUSCH PJ, WILSON SC, LEE AS, et al. Ancient origin of cGAS-STING reveals mechanism of universal 2', 3'cGAMP signaling[J]. Mol Cell, 2015, 59 (6) :891-903.
|
|
[10] OUYANG S, SONG X, WANG Y, et al. Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding[J]. Immunity, 2012, 36 (6) :1073-1086.
|
|
[11] LIU X, WANG C. The emerging roles of the STING adaptor protein in immunity and diseases[J]. Immunology, 2016, 147 (3) :285-291.
|
|
[12] WARNER JD, IRIZARRYCARO RA, BENNION BG, et al. STINGassociated vasculopathy develops independently of IRF3 in mice[J]. J Exp Med, 2017, 214 (11) :3279-3292.
|
|
[13] DAHAL LN, DOU L, HUSSAIN K, et al. STING activation reverses lymphoma-mediated resistance to antibody immunotherapy[J]. Cancer Res, 2017, 77 (13) :3619-3631.
|
|
[14] OGAWA E, MUKAI K, SAITO K, et al. The binding of TBK1 to STING requires exocytic membrane traffic from the ER[J].Biochem Biophys Res Commun, 2018, 503 (1) :138-145.
|
|
[15] TAKASHIMA K, OSHIUMI H, MATSUMOTO M, et al. TICAM-1 is dispensable in STING-mediated innate immune responses in myeloid immune cells[J]. Biochem Biophys Res Commun, 2018, 499 (4) :985-991.
|
|
[16] CUI X, CLARK DN, LIU K, et al. Viral DNA-dependent induction of innate immune response to hepatitis B virus in immortalized mouse hepatocytes[J]. J Virol, 2015, 90 (1) :486-496.
|
|
[17] THOMSEN MK, NANDAKUMAR R, STADLER D, et al. Lack of immunological DNA sensing in hepatocytes facilitates hepatitis B virus infection[J]. Hepatology, 2016, 64 (3) :746-759.
|
|
[18] SAITOH T, FUJITA N, HAYASHI T, et al. Atg9a controls dsDNA-driven dynamic translocation of sting and the innate immune response[J]. Proc Natl Acad Sci U S A, 2010, 106 (3) :20842-20846.
|
|
[19] KONNO H, KONNO K, BARBER GN. Cyclic di nucleotides trigger ULK1 (ATG1) phosphorylation of STING to prevent sustained innate immune signaling[J]. Cel, 2013, 155 (3) :688-698.
|
|
[20] ISHIKAWA H, BARBER GN. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling[J]. Cytokine, 2009, 48 (1-2) :674-678.
|
|
[21] WATSON RO, MANZANILLO PS, COX JS. Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway[J]. Cell, 2012, 150 (4) :803-815.
|
|
[22] ISHIKAWA H, BARBER GN. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling[J]. Nature, 2008, 455 (7213) :674-678..
|
|
[23] ISHIKAWA H, MA Z, BARBER GN. STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity[J]. Nature, 2009, 461 (7265) :788-792..
|
|
[24] LUO WW, LI S, LI C, et al. iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING[J]. Nat Immunol, 2016, 17 (9) :1057-1066.
|
|
[25] ZEVINI A, OLAGNIER D, HISCOTT J. Crosstalk between cytoplasmic RIG-I and STING sensing pathways[J]. Trends Immunol, 2017, 38 (3) :194-205.
|
|
[26] KWON D, SESAKI H, KANG SJ. Intracellular calcium is a rheostat for the STING signaling pathway[J]. Biochem Biophys Res Commun, 2018, 500 (2) :497-503.
|
|
[27] THOMSEN MK, NANDAKUMAR R, STADLER D, et al. Lack of immunological DNA sensing in hepatocytes facilitates hepatitis B virus infection[J]. Hepatology, 2016, 64 (3) :746-759.
|
|
[28] MA Z, DAMANIA B. The cGAS-STING defense pathway and its counteraction by viruses[J]. Cell Host Microbe, 2016, 19 (2) :150-158.
|
|
[29] GALLUZZI L, VANPOUILLE-BOX C, BAKHOUM SF, et al.SnapShot:CGAS-STING signaling[J]. Cell, 2018, 173 (1) :276-276. e1.
|
|
[30] ZHANG J, HU MM, WANG YY, et al. TRIM32 protein modulates type I interferon induction and cellular antiviral response by targeting MITA/STING protein for K63-linked ubiquitination[J]. J Biol Chem, 2012, 287 (34) :28646-28655.
|
|
[31] WANG Q, LIU X, CUI Y, et al. AMFR and INSIG1 bridge adaptor STING and kinase TBK1 by catalyzing K27-linked polyubiquitination of STING on endoplasmic reticulum[J]. Immunity, 2014, 6 (41) :919-933.
|
|
[32] CHEN Q, SUN L, CHEN ZJ. Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing[J]. Nat Immunol, 2016, 17 (10) :1142-1149.
|
|
[33] PEI RJ, CHEN XW, LU MJ. Control of hepatitis B virus replication by interferons and Toll-like receptor signaling pathways[J]. World J Gastroenterol, 2014, 20 (33) :11618-11629.
|
|
[34] BAI J, CERVANTES C, LIU J, et al. DsbA-L prevents obesity-induced inflammation and insulin resistance by suppressing the mt DNA release-activated cGAS-cGAMP-STING pathway[J]. Proc Natl Acad Sci U S A, 2017, 114 (46) :12196-12201.
|
|
[35] THOMSEN MK, NANDAKUMAR R, STADLER D, et al. Lack of immunological DNA sensing in hepatocytes facilitates hepatitis B virus infection[J]. Hepatology, 2016, 64 (3) :746-759.
|
|
[36] ANGHELINA D, LAM E, FALCKPEDERSEN E. Diminished antiviral innate response to Adenovirus vectors in cGAS/STING deficient mice minimally impacts adaptive immunity[J]. J Virol, 2016, 90 (13) :5915.
|
|
[37] GUO F, TANG L, SHU S, et al. Activation of STING in hepatocytes suppresses the replication of hepatitis B virus[J]. Antimicrob Agents Chemother, 2017, 61 (10) :e00771-17.
|
|
[38] LEI Z, DENG M, YI Z, et al. cGAS-mediated autophagy protects the liver from ischemia/reperfusion injury independent of STING[J]. Am J Physiol Gastrointest Liver Physiol, 2018, 314 (6) :g655-g667.
|
|
[39] GUO F, HAN Y, ZHAO X, et al. STING agonists induce an innate antiviral immune response against hepatitis B virus[J].Antimicrob Agents Chemother, 2015, 59 (2) :1273-1281.
|
|
[40] GUO X, CHANG S, LI H, et al. Cyclic GMP-AMP ameliorates diet-induced metabolic dysregulation and regulates proinflammatory responses distinctly from STING activation[J]. Sci Rep, 2017, 7 (1) :6355.
|
|
[41] HWANG J, KANG T, LEE J, et al. Design, synthesis, and biological evaluation of C7-functionalized DMXAA derivatives as potential human-STING agonists[J]. Org Biomol Chem, 2019, 17 (7) :1869-1874.
|
|
[42] ZHENG LB, WANG J, MAO Y, et al. A novel stimulator of interferon gene (STING) from Larimichthys crocea and their involvement in immune response to ectoparasite Cryptocaryon irritans infection[J]. Fish Shellfish Immunol, 2017, 71:239-245.
|
|
[43] KIM S, LI L, MALIGA Z, et al. Anticancer flavonoids are mouse selective STING agonists[J]. ACS Chem Biol, 2013, 8 (7) :1396-1401.
|
|
[44] IWASAKI A, MEDZHITOV R. Regulation of adaptive immunity by the innate immune system[J]. Science, 2010, 327 (5963) :291-295.
|
|
[45] LIU S, ZHAO K, SU X, et al. MITA/STING and its alternative splicing isoform MRP restrict hepatitis B virus replication[J].PLo S One, 2017, 12 (1) :e0169701.
|
|
[46] BAI J, CERVANTES C, LIU J, et al. DsbA-L prevents obesity-induced inflammation and insulin resistance by suppressing the mt DNA release-activated cGAS-cGAMP-STING pathway[J]. Proc Natl Acad Sci U S A, 2017, 114 (46) :12196-12201.
|
|
[47] CERBONI S, JEREMIAH N, GENTILI M, et al. Intrinsic antiproliferative activity of the innate sensor STING in T lymphocytes[J]. J Exp Med, 2017, 214 (6) :1769-1785.
|
|
[48] IRACHETA-VELLVE A, PETRASEK J, GYONGYOSI B, et al.Endoplasmic reticulum stress-induced hepatocellular death pathways mediate liver injury and fibrosis via Stimulator of Interferon Genes[J]. J Biol Chem, 2016, 291 (52) :26794.
|
|
[49] KRIZHANOVSKY V, YON M, DICKINS RA, et al. Senescence of activated stellate cells limits liver fibrosis[J]. Cell, 2008, 134 (4) :657-667.
|
|
[50] PETRASEK J, IRACHETAVELLVE A, CSAK T, et al. STINGIRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease[J]. PNAS, 2013, 110 (41) :16544-16549.
|
|
[51] IRACHETA-VELLVE A, PETRASEK J, GYONGYOSI B, et al.Endoplasmic reticulum stress-induced hepatocellular death pathways mediate liver injury and fibrosis via stimulator of interferon genes[J]. J Biol Chem, 2016, 291 (52) :26794-26805.
|
|
[52] IURESCIA S, FIORETTI D, RINALDI M. Targeting cytosolic nucleic acid-sensing pathways for cancer immunotherapies[J]. Front Immunol, 2018, 9:711.
|
|
[53] SANDRA IURESCIA DF, RINALDI M. Nucleic acid sensing machinery:Targeting innate immune system for cancer therapy[J]. Recent Pat Anticancer Drug Discov, 2018, 13 (1) :2-17.
|
|
[54] GADKAREE SK, FU J, SEN R, et al. Induction of tumor regression by intratumoral STING agonists combined with anti–programmed death-L1 blocking antibody in a preclinical squamous cell carcinoma model[J]. Head Neck, 2017, 39 (6) :1086-1094.
|
|
[55] TANG CA, ZUNDELL JA, RANATUNGA S, et al. Agonistmediated activation of STING induces apoptosis in malignant B cells[J]. Cancer Res, 2016, 76 (8) :2137-2152.
|
|
[56] FU J, KANNE DB, LEONG M, et al. STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade[J]. Sci Transl Med, 2015, 7 (283) :283ra52.
|
|
[57] ZEVINI A, OLAGNIER D, HISCOTT J. Crosstalk between cytoplasmic RIG-I and STING sensing pathways[J]. Trends Immunol, 2017, 38 (3) :194-205.
|
|
[58] KHOO LT, CHEN LY. Role of the cGAS-STING pathway in cancer development and oncotherapeutic approaches[J].EMBO Rep, 2018, 19 (12) :e46935.
|
|
[59] GLÜCK S, GUEY B, GULEN MF, et al. Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence[J]. Nat Cell Biol, 2017, 19 (9) :1061-1070.
|
|
[60] DOU Z, GHOSH K, VIZIOLI MG, et al. Cytoplasmic chromatin triggers inflammation in senescence and cancer[J]. Nature, 2017, 550 (7676) :402-406.
|
|
[61] BU Y, LIU F, JIA QA, et al. Decreased expression of TMEM173predicts poor prognosis in patients with hepatocellular carcinoma[J]. PLo S One, 2016, 11 (11) :e0165681.
|
|
[62] LI T, CHEN ZJ. The cGAS-cGAMP-STING pathway connects DNA damage to inflammation, senescence, and cancer[J]. J Exp Med, 2018, 215 (5) :1287-1299.
|
|
[63] GALLUZZI L, BUQUA, KEPP O, et al. Immunogenic cell death in cancer and infectious disease[J]. Nat Rev Immunol, 2017, 17 (2) :97-111.
|
DownLoad: