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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 36 Issue 2
Feb.  2020
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Article Contents

Research advances in fecal microbiota transplantation for the treatment of HBeAg-positive chronic hepatitis B

DOI: 10.3969/j.issn.1001-5256.2020.02.039
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  • Received Date: 2019-09-23
  • Published Date: 2020-02-20
  • HBeAg seroconversion is an important process during antiviral therapy for patients with HBeAg-positive chronic hepatitis B( CHB),while the first-line antiviral drugs,such as entecavir and tenofovir disoproxil fumarate,tend to have low HBeAg clearance rate and/or seroconversion rate,and at present,there is still a lack of effective radical treatment regimens. Latest studies have shown that fecal microbial transplantation( FMT) can induce HBeAg clearance in HBeAg-positive CHB patients receiving long-term antiviral therapy.This article reviews the research advances in the role of FMT in inducing HBeAg clearance in HBeAg-positive CHB patients and points out that FMT may become a new treatment regimen for HBeAg-positive CHB patients.

     

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