中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 36 Issue 10
Oct.  2020
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Article Contents

Mechanism of mitochondrial dysfunction in the development of nonalcoholic fatty liver disease

DOI: 10.3969/j.issn.1001-5256.2020.10.042
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  • Received Date: 2020-04-24
  • Published Date: 2020-10-20
  • Nonalcoholic fatty liver disease( NAFLD) includes a series of diseases affected by various complex factors. Mitochondrial dysfunction often occurs in NAFLD and may lead to the progression of hepatitis and liver fibrosis. This article reviews the important role of mitochondrial oxidative stress,respiration,energy metabolism,quality control,and mitochondrial DNA in NAFLD and summarizes the current status of mitochondria-targeted therapy for NAFLD,hoping to provide a new direction for the research and clinical treatment of NAFLD.

     

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