Pay attention to the multimodality therapy and long-term management for liver cirrhosis

Liver cirrhosis is the end-stage of various liver diseases including chronic hepatitis B, hepatitis C, alcoholic and nonalcoholic fatty liver diseases, with the main manifestations of hepatocyte dysfunction, portal hypertension and a series of complications. A clinical diagnosis of liver cirrhosis can be made based on medical history and the results of endoscopy, radiology, biochemistry, and hematological tests. Etiology, disease stage, and liver function reserve should be clarified for the diagnosis of liver cirrhosis. Treatment should include etiological therapy, comprehensive supportive therapy, and measures for various complications, aiming to prolong survival and improve quality of life. Long-term follow-up should be performed to monitor disease progression, evaluate therapeutic efficacy.