Chronic hepatitis B virus infection with nonalcoholic fatty liver disease: Problems faced by antiviral therapy

Yanhua TANG; Xingyu LU; Jian SUN

doi:10.3969/j.issn.1001-5256.2021.07.004

Volume 37 Issue 7

Jul. 2021

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Article Navigation > Journal of Clinical Hepatology > 2021 > 37(7): 1508-1514

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Chronic hepatitis B virus infection with nonalcoholic fatty liver disease: Problems faced by antiviral therapy

DOI: 10.3969/j.issn.1001-5256.2021.07.004

State Key Laboratory of Organ Failure Research, Hepatology Unit, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China

Research funding:

National Science and Technology Major Project of China (2017ZX10202202);

National Natural Science Foundation of China (82070614);

National Natural Science Foundation of China (81871668);

Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program (2017BT01S131)

Received Date: 2021-06-08
Accepted Date: 2021-06-08
Published Date: 2021-07-20

Abstract

Abstract

With an increase in the incidence rate of nonalcoholic fatty liver diseases (NAFLD), chronic hepatitis B virus (HBV) infection with NAFLD has become more and more common in clinical practice. In case of elevated alanine aminotransferase, identification of the underlying cause and timely implementation of effective management can prevent disease progression to liver cirrhosis and reduce the risk of hepatocellular carcinoma. Up to now, there is still a lack of recommendation on the clinical management of patients with chronic HBV infection and NAFLD in Chinese and international guidelines. This article reviews the latest guidelines for chronic HBV infection with NAFLD and discusses the influence of NAFLD on the indication for antiviral therapy, clinical outcome, and long-term prognosis in patients with chronic HBV infection and NAFLD, so as to provide a reference for the clinical management of such patients.
- Hepatitis B Virus,
- Hepatitis B, Chronic,
- Non-alcoholic Fatty Liver Disease,
- Therapeutics

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References(45)

References

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Chronic hepatitis B virus infection with nonalcoholic fatty liver disease: Problems faced by antiviral therapy

DOI: 10.3969/j.issn.1001-5256.2021.07.004

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Chronic hepatitis B virus infection with nonalcoholic fatty liver disease: Problems faced by antiviral therapy

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