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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 37 Issue 7
Jul.  2021
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Article Navigation >  Journal of Clinical Hepatology  > 2021  >  37(7): 1648-1651

Value of contrast-enhanced endoscopic ultrasound versus contrast-enhanced computed tomography in the diagnosis of pancreatic solid space-occupying lesions

DOI: 10.3969/j.issn.1001-5256.2021.07.033

  • Department of Gastroenterology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China

Research funding:

Capital Research Funds for Medical Development (Capital Development 2020-1-2042)

  • Received Date: 2020-12-05
  • Accepted Date: 2021-01-21
  • Published Date: 2021-07-20
    Abstract
  •   Objective  To investigate the value of contrast-enhanced endoscopic ultrasound (CE-EUS) versus contrast-enhanced computed tomography (CE-CT) in the diagnosis of pancreatic solid space-occupying lesions.  Methods  A total of 78 patients with pancreatic solid space-occupying lesions who attended Beijing Tiantan Hospital, Capital Medical University, from January 2014 to December 2019 were enrolled. All patients were diagnosed by EUS-guided fine needle aspiration or postoperative pathology, and CE-EUS and CE-CT were compared in terms of their accuracy, sensitivity, specificity, and Youden index in the diagnosis of pancreatic solid space-occupying lesions.  Results  In the diagnosis of pancreatic cancer, CE-EUS and CE-CT had accuracy rates of 97.9% and 87.2%, sensitivities of 97.7% and 88.9%, specificities of 100% and 50%, and Youden indices of 0.96 and 0.76, respectively. In the diagnosis of small pancreatic cancer, CE-EUS and CE-CT had accuracy rates of 84.6% and 61.5%, sensitivities of 80% and 70%, specificities of 100% and 33.3%, and Youden indices of 0.80 and 0.03, respectively. In the diagnosis of chronic pancreatitis with mass, CE-EUS and CE-CT had accuracy rates of 90.5% and 61.9%, sensitivities of 94.1% and 64.7%, specificities of 75% and 50%, and Youden indices of 0.69 and 0.15, respectively. In the diagnosis of pancreatic neuroendocrine tumors, CE-EUS and CE-CT had accuracy rates of 85.7% and 28.6%, sensitivities of 83.3% and 16.7%, specificities of 100% and 100%, and Youden indices of 0.83 and 0.17, respectively.  Conclusion  CE-EUS has certain advantages over CE-CT in the diagnosis of pancreatic solid space-occupying lesions.

     

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