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ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 37 Issue 7
Jul.  2021
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Article Navigation >  Journal of Clinical Hepatology  > 2021  >  37(7): 1708-1712

Influence of estrogen deficiency on metabolic associated fatty liver disease in postmenopausal women

DOI: 10.3969/j.issn.1001-5256.2021.07.049
  • 1.

    The First Clinical Medical College, Henan University of Traditional Chinese Medicine, Zhengzhou 450046, China

  • 2.

    Department of Hepatology and Spleen-Stomach, The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou 450000, China

Research funding:

National Natural Science Foundation of China(General Program) (81473651);

Science and Technology Key Project of Henan Province (202102310495)

  • Received Date: 2020-11-18
  • Accepted Date: 2021-01-05
  • Published Date: 2021-07-20
    Abstract
  • Epidemiological data have shown that postmenopausal women have a significantly higher incidence rate of metabolic associated fatty liver disease (MAFLD) than premenopausal women and men of the same age. Aiming at this phenomenon, this article summarizes the potential influence mechanism of estrogen deficiency on MAFLD in postmenopausal women from the four aspects of insulin resistance, liver lipid metabolism, liver fibrosis, and intestinal flora, so as to provide a reference for the early clinical prevention and treatment of MAFLD in postmenopausal women.

     

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