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CN 22-1108/R
Volume 37 Issue 8
Aug.  2021
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Article Navigation >  Journal of Clinical Hepatology  > 2021  >  37(8): 1905-1906

Type 1 diabetes mellitus due to pegylated interferon treatment of chronic hepatitis B: A case report

DOI: 10.3969/j.issn.1001-5256.2021.08.031
  • 1.

    Department of Endocrinology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing 100039, China

  • 2.

    Department of Internal Medicine, Hospital of Army 95968 of PLA, Beijing 100195, China

Research funding:

The Innovation Fund Youth Cultivation Project (QNPY2015008)

  • Received Date: 2020-11-29
  • Accepted Date: 2021-01-19
  • Published Date: 2021-08-20
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    • References(6)
  • [1]
    FABRIS P, BETTERLE C, FLOREANI A, et al. Development of type 1 diabetes mellitus during interferon alfa therapy for chronic HCV hepatitis[J]. Lancet, 1992, 340: 548. DOI: 10.1016/0140-6736(92)91744-s.
    [2]
    NEGRO F. Adverse effects of drugs in the treatment of viral hepatitis[J]. Best Pract Res Clin Gastroenterol, 2010, 24(2): 183-192. DOI: 10.1016/j.bpg.2009.10.012.
    [3]
    ZORNITZKI T, MALNICK S, LYSYY L, et al. Interferon therapy in hepatitis C leading to chronic type 1 diabetes[J]. World J Gastroenterol, 2015, 21(1): 233-239. DOI: 10.3748/wjg.v21.i1.233.
    [4]
    WAGURI M, HANAFUSA T, ITOH N, et al. Occurrence of IDDM during interferon therapy for chronic viral hepatitis[J]. Diabetes Res Clin Pract, 1994, 23(1): 33-26. DOI: 10.1016/0168-8227(94)90124-4.
    [5]
    SUKRAN K, GOZAYDIN A, AKKOCLU G, et al. Chronic hepatitis B with type I diabetes mellitus and autoimmune thyroiditis development during interferon alpha therapy[J]. Infect Dev Ctries, 2012, 6(4): 364-368. DOI: 10.3855/jidc.1632.
    [6]
    LV Y, SHI BY, GUO H. Abrupt onset of type 1 diabetes mellitus during recombinant interferon-alpha 2b therapy in a patient with chronic hepatitis B[J]. World J Gastroenterol, 2008, 14(29): 4713-4715. DOI: 10.3748/wjg.14.4713.
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