中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 37 Issue 8
Aug.  2021
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Article Contents

Current status of the surgical treatment of hepatic alveolar echinococcosis

DOI: 10.3969/j.issn.1001-5256.2021.08.047
Research funding:

National Key Research and Development Program of China (2017YFC0909900);

Qinghai Key Science and Technology Program (2020-ZJ-Y01)

  • Received Date: 2020-12-31
  • Accepted Date: 2021-01-22
  • Published Date: 2021-08-20
  • Hepatic alveolar echinococcosis (HAE) is a zoonotic disease caused by Echinococcus multilocularis. At present, the treatment of HAE is mainly based on radical surgical resection, assisted by drug therapy. This article introduces the current status of the application of radical surgical resection, ablation techniques, and palliative surgery in the treatment of HAE and summarizes the main indications for autologous liver transplantation, so as to provide certain experience and reference for selecting the treatment strategies for HAE.

     

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  • [1]
    WANG Z, WANG X, LIU X. Echinococcosis in China, a review of the epidemiology of Echinococcus spp[J]. Ecohealth, 2008, 5(2): 115-126. DOI: 10.1007/s10393-008-0174-0.
    [2]
    WU DB, CHEN EQ, BAI L, et al. Liver biopsy and related techniques in pathological diagnosis[J]. J Clin Hepatol, 2018, 34(11): 2295-2299. DOI: 10.3969/j.issn.1001-5256.2018.11.006.

    吴东波, 陈恩强, 白浪, 等. 肝穿刺活组织检查及病理学诊断中的相关技术及应用[J]. 临床肝胆病杂志, 2018, 34(11): 2295-2299. DOI: 10.3969/j.issn.1001-5256.2018.11.006.
    [3]
    Chinese Doctor Association, Chinese College of Surgeons (CCS), Chinese Committee for Hadytidology (CCH). Expert consensus on diagnosis and treatment of hepatic cystic and alveolar echinococcosis (2019 edition)[J]. Chin J Dig Surg, 2019, 18(8): 711-721. DOI: 10.3760/cma.j.issn.1673-9752.2019.08.002.

    中国医师协会外科医师分会包虫病外科专业委员会. 肝两型包虫病诊断与治疗专家共识(2019版)[J]. 中华消化外科杂志, 2019, 18(8): 711-721. DOI: 10.3760/cma.j.issn.1673-9752.2019.08.002.
    [4]
    KAMIYAMA T. Recent advances in surgical strategies for alveolar echinococcosis of the liver[J]. Surg Today, 2020, 50(11): 1360-1367. DOI: 10.1007/s00595-019-01922-6.
    [5]
    CHEN ZY. Surgical treatment of complicated hepatic echinococcosis[J]. Chin J Bases Clin Gen Surg, 2017, 24(7): 785-787. DOI: 10.7507/1007-9424.201705115.

    陈哲宇. 复杂肝包虫病的外科治疗[J]. 中国普外基础与临床杂志, 2017, 24(7): 785-787. DOI: 10.7507/1007-9424.201705115.
    [6]
    BRUNETTI E, KERN P, VUITTON DA, et al. Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans[J]. Acta Trop, 2010, 114(1): 1-16. DOI: 10.1016/j.actatropica.2009.11.001.
    [7]
    HILLENBRAND A, GRUENER B, KRATZER W, et al. Impact of safe distance on long-term outcome after surgical therapy of alveolar echinococcosis[J]. World J Surg, 2017, 41(4): 1012-1018. DOI: 10.1007/s00268-016-3813-6.
    [8]
    WEN H. Advancement of diagnosis and surgical treatment for hepatic echinococcosis[J]. Chin J Dig Surg, 2011, 10(4): 290-292. DOI: 10.3760/cma.j.issn.1673-9752.2011.04.014.

    温浩. 肝包虫病诊断和手术治疗新进展[J]. 中华消化外科杂志, 2011, 10(4): 290-292. DOI: 10.3760/cma.j.issn.1673-9752.2011.04.014.
    [9]
    WANG WT, YANG C, YAN LN. New concepts and strategies for radical surgical treatment of hepatic alveolar echinococcosis[J]. Natl Med J China, 2018, 98(38): 3049-3051. DOI: 10.3760/cma.j.issn.0376-2491.2018.38.001.

    王文涛, 杨闯, 严律南. 肝泡型包虫病外科根治性治疗的新理念与策略[J]. 中华医学杂志, 2018, 98(38): 3049-3051. DOI: 10.3760/cma.j.issn.0376-2491.2018.38.001.
    [10]
    GRUTTADAURIA S, VASTA F, MINERVINI MI, et al. Significance of the effective remnant liver volume in major hepatectomies[J]. Am Surg, 2005, 71(3): 235-240. http://www.ncbi.nlm.nih.gov/pubmed/15869140
    [11]
    SHEN HD, CHEN KF, LI B, et al. Two-stage hepatectomy for multiple giant alveolar echinococcosis[J]. Medicine (Baltimore), 2017, 96(33): e7819. DOI: 10.1097/MD.0000000000007819.
    [12]
    YANG C, HE J, YANG X, et al. Surgical approaches for definitive treatment of hepatic alveolar echinococcosis: Results of a survey in 178 patients[J]. Parasitology, 2019, 146(11): 1414-1420. DOI: 10.1017/S0031182019000891.
    [13]
    BRUNETTI E, FILICE C. Radiofrequency thermal ablation of echinococcal liver cysts[J]. Lancet, 2001, 358(9291): 1464. DOI: 10.1016/S0140-6736(01)06518-7.
    [14]
    CAIRANG Y, ZHANG L, REN B, et al. Efficacy and safety of ultrasound-guided percutaneous microwave ablation for the treatment of hepatic alveolar echinococcosis: A preliminary study[J]. Medicine (Baltimore), 2017, 96(27): e7137. DOI: 10.1097/MD.0000000000007137.
    [15]
    GU XB, WANG ZX, FAN HN, et al. Ultrasound-guided microwave ablation versus surgical resection for the treatment of early alveolar hepatic echinococcosis: Comparison of curative effect[J]. J Intervent Radiol, 2019, 28(12): 1151-1155. DOI: 10.3969/j.issn.1008-794X.2019.012.008.

    顾贤波, 王志鑫, 樊海宁, 等. 超声引导下微波消融与手术切除治疗早期泡型肝包虫病疗效对比[J]. 介入放射学杂志, 2019, 28(12): 1151-1155. DOI: 10.3969/j.issn.1008-794X.2019.012.008.
    [16]
    WEN H, DONG JH, ZHANG JH, et al. Ex vivo liver resection followed by autotransplantation for end-stage hepatic alveolar echinococcosis[J]. Chin Med J (Engl), 2011, 124(18): 2813-2817. http://www.cqvip.com/QK/85656X/201118/39394317.html
    [17]
    SHEN S, KONG J, ZHAO J, et al. Outcomes of different surgical resection techniques for end-stage hepatic alveolar echinococcosis with inferior vena cava invasion[J]. HPB (Oxford), 2019, 21(9): 1219-1229. DOI: 10.1016/j.hpb.2018.10.023.
    [18]
    SHEN S, KONG J, QIU Y, et al. Ex vivo liver resection and autotransplantation versus allotransplantation for end-stage hepatic alveolar echinococcosis[J]. Int J Infect Dis, 2019, 79: 87-93. DOI: 10.1016/j.ijid.2018.11.016.
    [19]
    AJI T, DONG JH, SHAO YM, et al. Ex vivo liver resection and autotransplantation as alternative to allotransplantation for end-stage hepatic alveolar echinococcosis[J]. J Hepatol, 2018, 69(5): 1037-1046. DOI: 10.1016/j.jhep.2018.07.006.
    [20]
    YANG X, QIU Y, HUANG B, et al. Novel techniques and preliminary results of ex vivo liver resection and autotransplantation for end-stage hepatic alveolar echinococcosis: A study of 31 cases[J]. Am J Transplant, 2018, 18(7): 1668-1679. DOI: 10.1111/ajt.14621.
    [21]
    CHAPUIS Y, HOUSSIN D, BROUZES S, et al. Hepatic transplantation in alveolar echinococcosis. 3 attempts[J]. Chirurgie, 1987, 113(6): 634-640.
    [22]
    KOCH S, BRESSON-HADNI S, MIGUET JP, et al. Experience of liver transplantation for incurable alveolar echinococcosis: A 45-case European collaborative report[J]. Transplantation, 2003, 75(6): 856-863. DOI: 10.1097/01.TP.0000054230.63568.79.
    [23]
    BRESSON-HADNI S, BLAGOSKLONOV O, KNAPP J, et al. Should possible recurrence of disease contraindicate liver transplantation in patients with end-stage alveolar echinococcosis? A 20-year follow-up study[J]. Liver Transpl, 2011, 17(7): 855-865. DOI: 10.1002/lt.22299.
    [24]
    NUNNARI G, PINZONE MR, GRUTTADAURIA S, et al. Hepatic echinococcosis: Clinical and therapeutic aspects[J]. World J Gastroenterol, 2012, 18(13): 1448-1458. DOI: 10.3748/wjg.v18.i13.1448.
    [25]
    KAWAMURA N, KAMIYAMA T, SATO N, et al. Long-term results of hepatectomy for patients with alveolar echinococcosis: A single-center experience[J]. J Am Coll Surg, 2011, 212(5): 804-812. DOI: 10.1016/j.jamcollsurg.2011.02.007.
    [26]
    QU B, GUO L, SHENG G, et al. Management of advanced hepatic alveolar echinococcosis: Report of 42 cases[J]. Am J Trop Med Hyg, 2017, 96(3): 680-685. DOI: 10.4269/ajtmh.16-0557.
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