Current status of research on elastography combined with serology in the diagnosis of chronic hepatitis B liver fibrosis

Qiao HE; Wencong YUAN; Haining FAN; He XU; Bin REN

doi:10.3969/j.issn.1001-5256.2021.12.037

Volume 37 Issue 12

Dec. 2021

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Article Navigation > Journal of Clinical Hepatology > 2021 > 37(12): 2914-2918

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Current status of research on elastography combined with serology in the diagnosis of chronic hepatitis B liver fibrosis

DOI: 10.3969/j.issn.1001-5256.2021.12.037

Qiao HE^{1, 2},
Wencong YUAN^{1, 2},
Haining FAN^{1, 2},
He XU^{1, 2},
Bin REN^{1, 2
,
,}

1.
Department of Hepatopancreatobiliary Surgery, Qinghai University Affiliated Hospital, Xining 810001, China
2.
Qinghai Province Key Laboratory of Hydatid Disease Research, Xining 810001, China

Research funding:

Qinghai Province Science and Technology Department Project (2020-ZJ-Y01)

Received Date: 2021-04-29
Accepted Date: 2021-05-20
Published Date: 2021-12-20

Abstract

Abstract

Liver biopsy is the gold standard for the diagnosis of liver fibrosis stage in patients with chronic hepatitis B, but it has certain limitations due to its invasiveness. At present, elastography and serological examination have the advantages of convenience, good repeatability, and dynamic testing and are thus widely used in clinical practice. The accuracy of testing has been supported by a large number of studies, and they have been gradually recommended by various guidelines and expert consensus. However, the diagnostic accuracy of the two methods is affected by factors such as inflammation, obesity, ascites, eating, and intercostal space stenosis, and elastography combined with serological examination can greatly improve the accuracy, sensitivity, and specificity of liver fibrosis staging. With reference to related articles in China and globally, this article reviews the problems of the two methods in the staging of chronic hepatitis B liver fibrosis.
- Liver Cirrhosis,
- Hepatitis B, Chronic,
- Elasticity Imaging Techniques,
- Biomarkers,
- Diagnosis

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References(45)

References

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Current status of research on elastography combined with serology in the diagnosis of chronic hepatitis B liver fibrosis

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Current status of research on elastography combined with serology in the diagnosis of chronic hepatitis B liver fibrosis

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