Role of microRNAs in the development and progression of nonalcoholic steatohepatitis

Xinyu AN; Lingxi HU; Jie QIAO; Rongqi WANG; Yuemin NAN

doi:10.3969/j.issn.1001-5256.2021.12.048

Volume 37 Issue 12

Dec. 2021

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Article Navigation > Journal of Clinical Hepatology > 2021 > 37(12): 2963-2966

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Role of microRNAs in the development and progression of nonalcoholic steatohepatitis

DOI: 10.3969/j.issn.1001-5256.2021.12.048

Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University, Shijiazhuang 050051, China

Research funding:

2020 Government-Funded Provincial-Level Clinical Medicine Outstanding Talent Training Project ;

Natural Science Foundation of Hebei Province (H2021206140)

Received Date: 2021-05-07
Accepted Date: 2021-07-05
Published Date: 2021-12-20

Abstract

Abstract

Nonalcoholic steatohepatitis (NASH) has become the second leading cause of hepatitis and can further progress to liver fibrosis, liver cirrhosis, and even liver cancer; however, the detailed pathogenesis of NASH remains unclear, and there is still a lack of effective therapeutic drugs. MicroRNAs (miRNAs) are a class of non-coding, post-transcriptionally regulated, and highly conserved small RNAs in the body and play an important role in a variety of liver diseases. This article mainly reviews the role of miRNAs in the development and progression of NASH.
- Nonalcoholic Steatohepatitis,
- MicroRNAs,
- Pathologic Processes

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References(39)

References

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Role of microRNAs in the development and progression of nonalcoholic steatohepatitis

DOI: 10.3969/j.issn.1001-5256.2021.12.048

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Role of microRNAs in the development and progression of nonalcoholic steatohepatitis

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