Role of G protein-coupled receptors in liver diseases

Rui CHEN; Kun ZHANG; Beichen GUO; Yuhan LI; Wei HONG; Tao HAN

doi:10.3969/j.issn.1001-5256.2022.07.042

Volume 38 Issue 7

Jul. 2022

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Article Navigation > Journal of Clinical Hepatology > 2022 > 38(7): 1677-1680

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Role of G protein-coupled receptors in liver diseases

DOI: 10.3969/j.issn.1001-5256.2022.07.042

Rui CHEN^{1, 2, 3},
Kun ZHANG⁴,
Beichen GUO^{1, 2, 3},
Yuhan LI^{1, 2, 3},
Wei HONG^{4
,
,
,},
Tao HAN^{1, 2, 3, 5
,
,
,}

1.
Department of Gastroenterology and Hepatology, Tianjin Union Medical Center, Tianjin Medical University, Tianjin 300121, China
2.
Department of Hepatology and Gastroenterology, The Third Central Clinical College of Tianjin Medical University, Tianjin 300170, China
3.
Department of Hepatology and Gastroenterology, The Third Central Hospital of Tianjin, Tianjin 300170, China
4.
Department of Histology and Embryology, School of Basic Medicine, Tianjin Medical University, Tianjin 300070, China
5.
Department of Gastroenterology and Hepatology, Tianjin Union Medical Center, Nankai University, Tianjin 300121, China

Research funding:

National Natural Science Foundation of China (81870429)

More Information

Corresponding author: HONG Wei, hongwei@tmu.edu.cn(ORCID: 0000-0003-1199-4365); HAN Tao, hantaomd@126.com(ORCID: 0000-0003-4216-6968)
Received Date: 2021-12-10
Accepted Date: 2022-01-07
Published Date: 2022-07-20

Abstract

Abstract

Chronic liver diseases greatly threaten the health of the Chinese people, and recent studies have found that some G protein-coupled receptors (GPCRs) and related signaling pathways are involved in the physiopathological processes of the liver and are associated with various liver diseases such as nonalcoholic fatty liver disease, liver cirrhosis, and liver cancer. This article reviews the association between GPCRs and liver diseases, so as to provide new strategies for the diagnosis and treatment of liver diseases.
- Receptors, G-Protein-Coupled,
- Non-alcoholic Fatty Liver Disease,
- Liver Cirrhosis,
- Carcinoma, Hepatocellular,
- Pathologic Processes

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References(35)

References

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Role of G protein-coupled receptors in liver diseases

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