Research advances in myosteatosis in chronic liver diseases

Jintao SUN; Fengxia LI

doi:10.3969/j.issn.1001-5256.2023.02.031

Volume 39 Issue 2

Feb. 2023

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Article Navigation > Journal of Clinical Hepatology > 2023 > 39(2): 444-449

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Research advances in myosteatosis in chronic liver diseases

DOI: 10.3969/j.issn.1001-5256.2023.02.031

Jintao SUN,
Fengxia LI^{,
,}

Department of Gastroenterology, The Fifth Clinical Medical College of Shanxi Medical University, Taiyuan 030012, China

Research funding:

Shanxi Province Key Medical Science and Technology Project (2020XM23)

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Corresponding author: LI Fengxia, doctorlfx@163.com (ORCID: 0000-0002-6712-0491)
Received Date: 2022-07-01
Accepted Date: 2022-08-12
Published Date: 2023-02-20

Abstract

Abstract

Myosteatosis is the main manifestation of malnutrition and is a common complication of chronic liver diseases, with a negative impact on the progression and prognosis of liver diseases. There is no gold standard for the diagnosis of myosteatosis, and CT is a commonly used diagnostic method. Myosteatosis in chronic liver diseases has diverse mechanisms, and hyperammonemia, increased cathepsin D level in circulation, insulin resistance, mitochondrial dysfunction, and chronic systemic microinflammation play an important role in myosteatosis. Early intervention of these factors can improve prognosis. With reference to related studies in China and globally, this article reviews the features, diagnostic methods, pathogenesis, treatment, and intervention of myosteatosis.
- Liver Diseases,
- Malnutrition,
- Myosteatosis,
- Pathological Conditions, Signs and Symptoms

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References(29)

References

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Research advances in myosteatosis in chronic liver diseases

DOI: 10.3969/j.issn.1001-5256.2023.02.031

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