Current research status of left-sided portal hypertension after superior mesenteric-portal vein confluence pancreaticoduodenectomy

Hong ZOU; Qiao ZHU; Yi WEN; Hongyin LIANG; Mingmei ZHOU; Kehui SHI; Jun WU; Lijun TANG

doi:10.3969/j.issn.1001-5256.2023.06.035

Volume 39 Issue 6

Jun. 2023

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Article Navigation > Journal of Clinical Hepatology > 2023 > 39(6): 1482-1487

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Current research status of left-sided portal hypertension after superior mesenteric-portal vein confluence pancreaticoduodenectomy

DOI: 10.3969/j.issn.1001-5256.2023.06.035

a.
Department of General Surgery, The General Hospital of Western Theater Command, Chengdu 610083, China
b.
Department of Obstetrics and Gynecology, The General Hospital of Western Theater Command, Chengdu 610083, China
c.
Trauma Center, The General Hospital of Western Theater Command, Chengdu 610083, China

Research funding:

National Clinical Key Specialty Military Construction Project (41732113);

Sichuan Provincial Science and Technology Department Planning Project (2019YJ0277)

More Information

Corresponding author: TANG Lijun, 360914763@qq.com (ORCID: 0000-0001-6000-9515)
Received Date: 2022-10-05
Accepted Date: 2022-11-26
Published Date: 2023-06-20

Abstract

Abstract

Surgical operation is the main treatment method for pancreatic cancer, and in clinical practice, radical surgery for pancreatic cancer is often combined with superior mesenteric-portal vein confluence pancreaticoduodenectomy to achieve R0 resection. However, severe left-sided portal hypertension (LSPH) may occur after splenic vein dissection, resulting in a series of pathological changes such as congestive splenomegaly, thrombocytopenia, backflow obstruction of splenic vein, and gastrointestinal varices, and in some cases, it can lead to fatal gastrointestinal hemorrhage and hemorrhagic shock. Therefore, in order to better manage LSPH in clinical practice, this article systematically analyzes and reviews the pathogenesis, treatment regimens, and control strategies of LSPH after combined superior mesenteric-portal vein confluence pancreaticoduodenectomy and put forward corresponding suggestions based on current studies.
- Pancreatic Neoplasms,
- Pancreaticoduodenectomy,
- Hypertension,
- Portal

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References(36)

References

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Current research status of left-sided portal hypertension after superior mesenteric-portal vein confluence pancreaticoduodenectomy

DOI: 10.3969/j.issn.1001-5256.2023.06.035

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Current research status of left-sided portal hypertension after superior mesenteric-portal vein confluence pancreaticoduodenectomy

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