重型肝炎患者血清sCR1与肝功能损伤程度的相关性研究

To study the changes and the clinical significance of serum complement receptor 1 (sCR1) of patients with hepatitis gravis. Enzyme-linked immuno-sorbent assay (ELISA) was used to analysis 30 cases with hepatitis gravis, 46 cases with chronic viral hepatitis and 30 control cases. It suggested that sCR1 of patients with hepatitis gravis or chronic viral hepatitis was significantly higher than that of the control group (P<0.01) . And sCR1 of patients with hepatitis gravis was significantly higher than that of patients with chronic viral hepatitis (P<0.01) , and was related with the changes of CHE, PT and PTA. It was concluded that the changes of sCR1 of hepatitis gravis was related with the damage degree of liver function, and it can be used as reference marker for analyzing of the degree of hepatitis gravis and judging the development and prognoses.