This study evaluates the relationship of Helicobacter pylori (H.pylori) infection and portal hypertensive gastropathy (PHG) in patients with liver cirrhosis. To detect H. pylori infectious rate by Urease test, 14 C urea breath test ( 14 C-UBT) and serological diagnostic test in 200 patients with portal hypertensive gastropathy (PHG) (50 cases) , liver cirrhosis (50 cases) , duodenal ulcer (50 cases) , and functional dyspepsia (50 cases) . Results showed H. pylori infectious rate was 36% (18/50) in patients with PHG and it is remarkably lower than that of patients with duodenal ulcer (94%) , but no clear difference in patients liver cirrhosis (38%) or functional dyspepsia (44%) . We consider that H. pylori infection seems to be unlikely in the pathogenesis of PHG.
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