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Issue 3
Mar.  2004
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Article Navigation >  Journal of Clinical Hepatology  > 2004  >  20(3): 159-160

酒精中毒患者血清中肝细胞再生因子水平的测定及其意义

  • Published Date: 2004-03-20
    Abstract
  • This study was done to investigate the change of hepatocyte growth factor in alcoholic intoxication patients and its signification. Tissue-cell culture and isotopelabeled technique were used to determine the difference of the hepatocyte growth factor in the blood serum between 30-alcoholic intoxication patients and 30-healthy control groups. The hepatocyte growth factor in the blood serum of acute alcoholic intoxication patients with severe hepatic injury was higher than that of chronic alcoholic intoxication patients with gentle hepatic injury (P<0.05) , and it was significantly higher than that of control groups (P<0.01) . Above results can provide reference criteria for estimating the level of hepatic injury in the alcoholic intoxication patients.

     

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    • References(5)
  • [1] 中华医学会精神科学会, 南京医科大学脑科医院编.中国神经精神疾病分类方案及诊断标准[M].南京:东南大学出版社, 1995∶49.
    [2] SeglenPO .Preparationofratlivercells.3.Enzymaticrequirementsfortissuedispersion[J].ExpCellRes, 1973, 82 (2) ∶391-8.
    [3]金哲洙.肝细胞再生因子的研究现状[J].延边医学院学报, 1991, 14 (3) ∶233.
    [4] 金哲洙, 董祥家, 韩厚哲, 等.各型肝炎血清中肝细胞再生因子水平的测定及其意义[J].中国实验与临床免疫学杂志, 1993, 5 (1) ∶24.
    [5] KinoshitaT , HiraoS , MatsumotoK , etal.Possibleendocrinecontrolbyhepatocytegrowthfactorofliverregenerationafterpartialhepatectomy[J].BiochemBiophysResCommun, 1991, 177 (1) ∶330-5.
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