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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 3
Mar.  2004
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肝内胆管癌细胞9810凋亡和bcl-2基因表达关系研究

  • Published Date: 2004-03-20
  • To investigate the relation between apoptosis of intrahepatic cholangiocarcinoma cell lines 9810 and expression of bcl-2 gene. We detect its apoptosis and expression of bcl-2 gene by flow cytometer. Apoptosis of intrahepatic cholangiocarcinoma was up step by step flowing Adriacin's concentration, expression of bcl-2 gene was down as well as it. Influencing expression of bcl-2 gene may be a reason of apoptosis of intrahepatic cholangiocarcinoma cell.

     

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  • [1]何振平.肝内胆管癌的临床病理特征、诊断及治疗[J].中国普外基础与临床杂志, 2001, 8 (2) ∶125-127.
    [2]金凯, 叶山仰.肝内胆管癌24例[J].浙江肿瘤, 1998, 4 (2) ∶121.
    [3] OkaroAC , FennellDA , CorboM , etal.Pk11195, amitochondrialben zodiazepinereceptorantagonist, reducesapoptosisthresholdinBcl-X (L) andMcl-1expressinghumancholangiocarcinomacells.Gut, 2002, 51 (4) ∶556-61.
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      沈阳化工大学材料科学与工程学院 沈阳 110142

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