中文English
ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 2
Feb.  2011
Turn off MathJax
Article Contents

Clinical analysis of 11 cases of hepatic veno-occlusive disease caused by Chinese herbal medicine

  • Received Date: 2010-11-29
  • Published Date: 2011-02-20
  • Objective TO assess a variety of routine detection methods for the value of clinical diagnosis of Hepatic veno-occlusive disease (HVOD) caused by Chinese herbal medicine and explore the evaluation method of disease outcome and prognosis.Methods According to retrospective study.we analyze the clinical manifestations, biochemical and imaging features of 11 cases with HVOD in our hospital in the last three years.Results All patients have a clear medical history, 7 cases taking the Gynura Rhizome, 2 cases taking the Common Threewingnut Root, 2 cases taking unknown Chinese herbal medicine.CT plays an important role in the diagnosis of HVOD, all 4 deaths are severe patients.Conclusion The diagnosis of HVOD should pay attention to the medication history of patients, The classification of HVOD patients is important to assess the disease.

     

  • loading
  • [1]Chen Z, Huo JR.Hepatic veno-occlusive disease associated with toxicity of pyrrolizidine alkaloids in herbal preparations[J].Neth J Med, 2010, 68 (6) :252-260.
    [2]Cefalo MG, Maurizi P, Arlotta A, et al.Hepatic veno-occlusive disease:a chemotherapy-related toxicity in children with malignancies[J].Paediatr Drugs, 2010, 12 (5) :277-284.
    [3]吴国琳, 余国友, 陈玖.中药土三七致肝小静脉闭塞病临床分析[J].中国中药杂志, 2008, 33 (20) :2402-2404.
    [4]DeLeve LD, Shulman HM, McDonald GB.Toxic injury to hepatic sinusoids:sinusoidal obstruction syndrome veno-occlusive disease[J].Semin Liver Dis, 2002, 22 (1) :27-42.
    [5]Mc Donald GB, Hinds MS, Fisher ID, et al.Veno-occlusive disease of the liver and multiorgan failure after bone marrow transplantation a cohort study of 355 patients[J].Ann Intern Med, 1993, 118 (4) :255-267.
    [6]陈毅鹏, 李君, 柴菊爱, 等.肝静脉闭塞病的临床和病理研究[J].中华消化杂志, 2006, 26 (4) :224-226.
    [7]Jones RJ, Lee KSK, Beschomer WE, et al.Veno-occlusive disease of the liver following bone marrow transplantation[J].Transplantation, 1987, 44 (6) :778-783.
    [8]Mc Donald GB, Sharma P, Matthews DE, et al.Veno-occlusive disease of the liver after bone marrow transplantation:diagnosis, incidence and predisposing factors[J].Hepatology, 1984, 4:116-122.
    [9]Matsumoto Y, Horiike S, Sakagami J, et al.Early ultrasonographic diagnosis and clinical follow-up of hepatic veno-occlusive disease after allogeneic bone marrow transplantation in a patient with acute lymphoblastic leukemia[J].Intern Med, 2009, 48 (10) :831-835.
    [10]Pei YG, Hu DY, Shen YQ, et al.The value of MSCT and MRI in the diagnosis of hepatic veno-occlusive disease[J].Zhonghua Gan Zang Bing Za Zhi, 2010, 18 (2) :150-152.
    [11]Richardson PG, Soiffer RJ, Antin JH.et al.Defibrotide for the treatment of severe hepatic veno-occlusive disease and multiorgan failure after stem cell transplantation:a multicenter, randomized, dose-finding trial[J].Biol Blood Marrow Transplant, 2010, 16 (7) :1005-1017.
  • 加载中

Catalog

    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (5045) PDF downloads(1358) Cited by()
    Proportional views
    Related

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return