Clinical analysis of relationship between gallstone morphology and biliary pancreatitis
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摘要: 目的探讨胆囊结石形态与急性胰腺炎的关系。方法收集2011年2月至2013年2月收治的110例胆源性胰腺炎患者作为胰腺炎组,110例胆囊结石患者作为非胰腺炎组。分析比较两组患者胆囊结石大小、数量、形状及质地与胰腺炎的关系。率的比较采用卡方检验。结果胰腺炎组与非胰腺炎组结石大小、数量、形状相比较差异具有统计学意义(χ2=41.146、27.150、13.839,P均<0.01);两组结石质地的比较差异有统计学意义(χ2=8.000,P<0.05);轻型和重型急性胰腺炎患者中结石<3 mm者分别为66.36%和86.67%,3~10 mm分别为17.89%和13.33%。结论相比较其他类型的结石,患者微小多发性、质软易碎的结石发生胰腺炎的几率增高;且结石越小,胰腺炎严重程度有增高的趋势。Abstract: Objective To investigate the relationship between gallstone morphology and acute pancreatitis. Methods A total of 110 patients with biliary pancreatitis, who were admitted to our hospital from February 2011 to February 2013, were selected as pancreatitis group, while 110 patients with gallstones were selected as non- pancreatitis group. The sizes, number, shapes, and textures of gallstones were compared between the two groups, and the relationship between gallstone morphology and pancreatitis was analyzed. Comparison between groups was made by chi- square test. Results There were significant differences in the sizes, number, and shapes of gallstones between the pancreatitis group and non- pancreatitis group ( χ2= 41. 146, 27. 150, and 13. 839, P < 0. 01 for all comparisons) . Stone texture also showed significant difference between the two groups ( χ2= 8. 000, P < 0. 05) . Of the patients with mild acute pancreatitis, 66. 36% had gallstone sizes of < 3 mm, and 17. 89% had gallstone sizes of 3- 10 mm; of the patients with severe acute pancreatitis, 86. 67% had gallstone sizes of < 3 mm, and 13. 33% had gallstone sizes of 3- 10 mm. Conclusion Among the patients with gallstones, those who have small, multiple, soft, and brittle stones have an increased incidence of pancreatitis; the decrease in stone sizes leads to an increasing trend in the severity of pancreatitis.
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Key words:
- pancreatitis /
- cholecystolithiasis
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