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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 10
Oct.  2013
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Article Contents

Research progress in magnetic nanoparticles for magnetic resonance imaging and targeted therapy of hepatocellular carcinoma

DOI: 10.3969/j.issn.1001-5256.2013.10.005
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  • Received Date: 2013-07-19
  • Published Date: 2013-10-20
  • Superparamagnetic iron oxide nanoparticles ( SPIONs) are new materials that have been widely used in medical imaging, targeted therapy, magnetic hyperthermia, etc. SPIONs can be used not only for specific diagnosis of early- stage hepatocellular carcinoma ( HCC) , but also as a desirable targeted drug nanocarrier. The properties of SPIONs as a targeted drug carrier, the principle of magnetic resonance imaging using SPIONs, and the action mechanism of SPIONs in targeting HCC are reviewed, with an emphasis on the surface modification and functionalization of SPIONs and their application in active targeted drug delivery system. It is believed that SPIONs will play a greater role in the diagnosis and treatment of HCC.

     

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