2013 No. 10

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Editorial

Current situation and prospect of interventional treatment of hepatocellular carcinoma

Guo QiYong, Wen Feng

2013, 29(10): 721-725. DOI: 10.3969/j.issn.1001-5256.2013.10.001

Abstract(2536)

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Abstract:
Hepatocellular carcinoma ( HCC) is one of the most refractory malignancies worldwide, and there are about 650 000 people who die of HCC each year around the world. Despite many treatment methods for HCC, the treatment outcome is still not satisfactory. At present, interventional treatment, represent...

Therapeutic guidelines

NASPGHAN practice guidelines: diagnosis and management of hepatitis C infection in infants, children, and adolescents

Zhu Peng, Wang YuMing

2013, 29(10): 726-731. DOI: 10.3969/j.issn.1001-5256.2013.10.002

Abstract(2318)

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Abstract:

Discussions by experts

Research progress in CT and MR for quantitative diagnosis of liver fibrosis

Yan FuHua, Luo XianFu

2013, 29(10): 732-735. DOI: 10.3969/j.issn.1001-5256.2013.10.003

Abstract(3272)

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Abstract:
Liver fibrosis is a repair response to liver damage caused by various factors, as well as an intermediate stage between chronic liver diseases and liver cirrhosis. The development of liver fibrosis is a latent, gradual, and reversible process. Timely, accurate diagnosis of liver fibrosis is of great...

Clinical application of liver- specific contrast agent Gd+- EOB- DTPA in progression assessment and early diagnosis of hepatocellular carcinoma

Ding Ying, Ceng MengSu

2013, 29(10): 736-739. DOI: 10.3969/j.issn.1001-5256.2013.10.004

Abstract(6179)

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Abstract:
Gd+- EOB- DTPA, a liver- specific contrast agent for magnetic resonance imaging ( MRI) , has intracellular and extracellular functions. The contrast agent can be absorbed into normal liver cells and excreted into the bile, with an absorption rate of about 50% and an excretion rate of about 50%. The ...

Research progress in magnetic nanoparticles for magnetic resonance imaging and targeted therapy of hepatocellular carcinoma

Gu Han, Li Cheng

2013, 29(10): 740-743. DOI: 10.3969/j.issn.1001-5256.2013.10.005

Abstract(3295)

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Abstract:
Superparamagnetic iron oxide nanoparticles ( SPIONs) are new materials that have been widely used in medical imaging, targeted therapy, magnetic hyperthermia, etc. SPIONs can be used not only for specific diagnosis of early- stage hepatocellular carcinoma ( HCC) , but also as a desirable targeted dr...

Research advances in proton beam therapy for hepatocellular carcinoma

Dai ShuYang, Huang Xing, Yang Tian, Shen Feng

2013, 29(10): 744-747. DOI: 10.3969/j.issn.1001-5256.2013.10.006

Abstract(3894)

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Abstract:
Hepatocellular carcinoma ( HCC) , one of the most common malignancies with high prevalence and mortality rate, usually results in poor prognosis and limited survival. A comprehensive analysis on the number and location of tumors, Child- Pugh grade, and Barcelona Clinic Liver Cancer stage will help t...

Interventional therapy for intractable cases of Budd- Chiari syndrome

Xu Hao

2013, 29(10): 748-751. DOI: 10.3969/j.issn.1001-5256.2013.10.007

Abstract(3230)

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Abstract:
Interventional therapy has become the preferred treatment for Budd- Chiari syndrome ( BCS) . The radiological diagnosis of BCS and the experience in diagnosing and treating six types of intractable BCS, i. e., hepatic vein occlusion, long segmental occlusion of the inferior vena cava ( IVC) , occlus...

Original articles_Radiation diagnostic and treatment for liver disease

Diagnostic value of LSM combined with APRI for liver fibrosis due to chronic hepatitis B

Feng Fei, Ma SuMei, Chen Fei, Yang DongHong, Yao YaNing, Wang Rui, Zhang XiaoYuan

2013, 29(10): 752-755. DOI: 10.3969/j.issn.1001-5256.2013.10.008

Abstract(4247)

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Abstract:

Objective To evaluate the diagnostic value of liver stiffness ( LS) combined with aspartate aminotransferase- to- platelet ratio index ( APRI) for liver fibrosis due to chronic hepatitis B. Methods One hundred and forty- seven patients with chronic hepatitis B admitted to our hospital from August 20...

Diagnostic value of acoustic radiation force impulse in patients with non- alcoholic simple fatty liver

Chen Fei, Yao YaNing, Ma SuMei, Feng Fei, Zou Quan, Xue LiLi

2013, 29(10): 756-759. DOI: 10.3969/j.issn.1001-5256.2013.10.009

Abstract(2941)

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Abstract:

Objective To investigate the value of acoustic radiation force impulse ( ARFI) in evaluating non- alcoholic simple fatty liver ( NAFL) . Methods Eighty- four patients with NAFL, who were admitted to our hospital from June to December 2011, were divided into mild, moderate, and severe NAFL groups acc...

Evaluation of anti- fibrosis effect of compound Biejia Ruangan tablets with transient elastography

Zhang Ning, Zhou ShuangNan, Gong Man, Song XueAi, Sun YongQiang, Jing Jing, Zhou Chao, Luo ShengQiang, Xiao XiaoHe

2013, 29(10): 760-763. DOI: 10.3969/j.issn.1001-5256.2013.10.010

Abstract(3324)

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Abstract:

Objective To evaluate the clinical efficacy of compound Biejia Ruangan tablets using transient elastography in patients with hepatitis B- induced compensated liver cirrhosis who are concurrently treated with entecavir. Methods In this prospective, randomized, and controlled study, 100 patients with ...

Sorafenib combined with thanscatheter artierial chemoembolzation in treatment of advanced hepatocellular carcinoma: Meta analysis

Yang Jun, Meng QingHua, Yu HongWei

2013, 29(10): 764-768. DOI: 10.3969/j.issn.1001-5256.2013.10.011

Abstract(3018)

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Abstract:

Objective To evaluate the effectiveness and toxicities of sorafenib combined with thanscatheter artierial chemoembolzation ( TACE) in the treatment of advanced hepatocellular carcinoma ( HCC) . Methods According to the Cochrane handbook for systematic review, two reviewers independently completed th...

Establishment of rat model of liver cirrhosis or liver cancer and its magnetic resonance images before and after superparamagnetic iron oxide enhancement

Huang RuiSui, Li Cheng, Gu Han, Jiao ZhiYun

2013, 29(10): 769-774. DOI: 10.3969/j.issn.1001-5256.2013.10.012

Abstract(3292)

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Abstract:

Objective To establish a rat model of liver cirrhosis or liver cancer, to determine the liver cancer detection rates of magnetic resonance imaging ( MRI) in liver cirrhosis before and after superparamagnetic iron oxide ( SPIO) enhancement, to analyse the changes in SPIO distribution in different les...

Original articles_Viral hepatitis

Liver stiffness becomes stable in patients with chronic hepatitis C three months after ALT normalization due to antiviral therapy

Chen FeiKai, Wei Lai, Feng Bo, Rao HuiYing

2013, 29(10): 775-779. DOI: 10.3969/j.issn.1001-5256.2013.10.013

Abstract(3063)

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Abstract:

Objective To investigate the time for liver stiffness measurement ( LSM) to become stable in chronic hepatitis C ( CHC) patients with elevated alanine aminotransferase ( ALT) levels after ALT normalization due to antiviral therapy. Methods CHC patients who sought initial treatment at Peking Universi...

Clinical efficacy of ribavirin combined with different doses of interferon α- 2b in patients with chronic hepatitis C genotypes 2 and 3

Zhao XiaoLing, Zhang YongGang

2013, 29(10): 780-783. DOI: 10.3969/j.issn.1001-5256.2013.10.014

Abstract(2838)

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Abstract:

Objective To investigate the clinical efficacy of ribavirin ( RBV) combined with different doses of interferonα-2b ( IFN α-2b) in patients with chronic hepatitis C genotypes 2 and 3. Methods Forty- six patients who were admitted for chronic hepatitis C genotypes 2 and 3 from April 2009 to January 20...

Original articles_Others

Central venous catheter- assisted abdominal drainage in treatment of intractable ascites: report of 36 cases

Guo HaiJun, Tong XueFei

2013, 29(10): 784-786. DOI: 10.3969/j.issn.1001-5256.2013.10.015

Abstract(2956)

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Abstract:

Objective To assess the therapeutic efficacy of central venous catheter placement via abdominal puncture in the treatment of refractory ascites. Methods Thirty- six patients with refractory ascites due to cirrhosis who were unresponsive to albumin supplement and diuretic treatment and admitted to ou...

Protective role of β- catenin gene in hepatic ischemia- reperfusion injury among mice and its mechanism

Sun KeYan, Teng Fei, Guo WenYuan, Liu Fang, Fu ZhiRen

2013, 29(10): 787-789. DOI: 10.3969/j.issn.1001-5256.2013.10.016

Abstract(2704)

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Abstract:

Objective To investigate the protective effect ofβ- catenin gene in hepatic ischemia- reperfusion injury among mice and the underlying mechanism. Methods Using β- catenin knockout mice and a segmental hepatic ischemia- reperfusion model, serum levels of alanine aminotransferase ( ALT) and aspartate ...

Case reports

One case of primary hepatic amyloidosis

Li Chen, Chen Jing, Liu HongLing, Zhu Bing, Zang Hong, You ShaoLi, Xin ShaoJie

2013, 29(10): 790-792. DOI: 10.3969/j.issn.1001-5256.2013.10.017

Abstract(1906)

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Abstract:

Reviews

Clinical application of perfusion- weighted MRI in liver diseases

Chen Juan, Yin HuaBin

2013, 29(10): 793-796. DOI: 10.3969/j.issn.1001-5256.2013.10.018

Abstract(2986)

PDF (1200KB)(608)

Abstract:
Conventional magnetic resonance imaging ( MRI) can provide the characteristics of abdominal solid tumors such as sizes and shapes, while perfusion- weighted imaging can provide additional information on the blood supply, vascular distribution, and vascular permeability of tumors. These information i...

HCV genetic heterogeneity and its host genetics

Nie YongHong, Xu ChunMei

2013, 29(10): 797-800. DOI: 10.3969/j.issn.1001-5256.2013.10.019

Abstract(2938)

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Abstract:
Hepatitis C represents a major worldwide public health problem. Studies have shown that both genetic diversity of hepatitis C virus ( HCV) and genetic polymorphisms of IL- 28B, ITPA, and IP- 10 in the host are implicated in the progression of hepatitis C, treatment response, and adverse effects. The...