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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 11
Nov.  2013
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Article Contents

Research progress in role of augmenter of liver regeneration in the liver

DOI: 10.3969/j.issn.1001-5256.2013.11.019
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  • Received Date: 2013-04-08
  • Published Date: 2013-11-20
  • Recent studies have found that augmenter of liver regeneration ( ALR) not only promotes liver regeneration and protects the liver from damage, but may also play an important role in the formation and development of the liver. The recent progress in research on the biological function and action mechanism of ALR in the liver is reviewed, and the application of ALR in the diagnosis and treatment of liver diseases is summarized. It is suggested that ALR may regulate hepatocyte apoptosis through the mitochondrial pathway to promote liver repair and regeneration. In the future, ALR may be used as a candidate for evaluating liver regeneration and prognosis in patients with liver failure.ALR holds promise as an effective medicine for treating severe liver disease and liver failure.

     

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