Research advances in diagnosis and treatment of adult hepatoblastoma

Adult hepatoblastoma is extremely rare in clinical practice,and its pathogenesis is unknown. At present,there is a lack of understanding of this disease,and therefore clinical misdiagnosis is common. This review introduces the pathogenesis,clinical manifestations,and radiological and pathological characteristics of hepatoblastoma,focuses on the choice of treatment for adult hepatoblastoma,and explains briefly the latest research progress in biological therapy. Comparison of different treatments suggests that comprehensive treatment based on radical resection is still the best choice. However,the curative effect is poor since the disease is highly malignant and its treatment experience is insufficient. The newly reported target for biological therapy may represent a breakthrough for the treatment of the disease,but its clinical efficacy remains to be evaluated. The pathogenesis of the disease in adults and children has not been confirmed as the same,and the review indicates that further clinical research is still needed.