Mother- to- child transmission( MTCT) is an important way of hepatitis B virus( HBV) transmission. Blocking the HBV MTCT has a great significance for the prevention and treatment of hepatitis B. This article reviews the current blocking strategies implemented in the antepartum,peripartum,and postpartum stages,and summarizes the controversies existing in the blocking strategies in different stages. The significance of HBV occult infection and germ cell transmission in the HBV MTCT is analyzed. The results indicate that the current strategies for the prevention of hepatitis B MTCT need further improvement. Attentions should be focused on HBV occult infection and germ cell transmission.
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