In recent years,the incidence of idiosyncratic drug- induced liver injury( IDILI) has been increasing,posing a threat to human health. This article reviews the incidence,pathogenesis,and the principles of clinical diagnosis and treatment of IDILI. Because there is limited literature on IDILI in children,so this article simply describes the experience in the diagnosis and treatment of IDILI in children. It is considered that to reduce the incidence of IDILI in children,drug indications should be strictly followed,and molecular test and accurate medical treatment should be promoted.
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