The hepatic nodular lesions in the progression of various chronic liver diseases are hot topics all the time. There is a close relationship between hepatic nodular lesions and hepatocellular carcinoma( HCC),and the former is the precancerous lesions of the latter. This paper summarizes the pathological features and imaging findings of hepatic nodular lesions,as well as the transition from hepatic nodular lesions to HCC. It is believed that early diagnosis and timely intervention are necessary.