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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Volume 32 Issue 1
Jan.  2016
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Article Contents

Application of CRISPR/Cas9 system in virus research

DOI: 10.3969/j.issn.1001-5256.2016.01.041
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  • Received Date: 2015-05-07
  • Published Date: 2016-01-20
  • To date,the clustered regularly interspaced short palindromic repeat( CRISPR) / Cas9 system has been widely used to edit the genome in many species and cells. The system is the third generation of artificial endonuclease,which can edit DNA by recognizing short DNA sequences. This paper reviews the structural features of the system and its application in virus research,such as the functional studies of virus- related genes and the exploration of antiviral therapies( including HIV,HBV,and EB virus),looking forward to the future direction of virus research.

     

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