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ISSN 1001-5256 (Print)
ISSN 2097-3497 (Online)
CN 22-1108/R
Issue 2
Feb.  2016
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Article Contents

Research advances in the pathogenesis of drug-induced liver injury

DOI: 10.3969/j.issn.1001-5256.2016.02.041
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  • Received Date: 2015-06-19
  • Published Date: 2016-02-20
  • In recent years,with an increasing number of drug types and unreasonable drug use,the incidence and mortality of drug- induced liver injury( DILI) have been increasing. The pathogenesis of DILI is complex,and may involve liver injury caused by the direct effect of drugs,immune- mediated liver injury,mitochondrial injury,and bile duct injury,etc. This article investigates the pathogenesis and its important role in the prevention and treatment of DILI,and reviews the research advances in the pathogenesis of DILI.

     

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